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Can Donepizil Worsen symptoms?

Asked for Female, 92 years

My elderly mother has been taking Donepezil for almost 4 years now. She is 92 now. When she first starting taking this medication her memory was getting spotty and her doctor (a general practitioner), put her on Donepizil. Her memory wasn't improving so he doubled the dose. Not only wasn't her memory improving, it seemed to be getting worse! She seemed more confused, withdrawn, and eve depressed. One day she didn't take and seemed much more "with it". Can this drug have adverse effects?

Responses (1)
Dr. Beenish Ehsan
Family Physician - Karachi

Dear Patient,

I'm sorry to hear this. Yes, any medicine can have side effects and cannot suit the patient. I would recommend taking a second opinion from a neurologist for her immediately.

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