Flagyl Tablet 400mg

About Flagyl Tablet 400mg

Flagyl Tablet Uses

• Treating amebic dysentery and intestinal amebiasis
• Managing giardiasis and giardia infections
• Treating trichomoniasis and urogenital infections
• Treating anaerobic bacterial infections
• Managing bacterial vaginosis and pelvic infections

Flagyl Tablet Benefits

• Effective against both parasitic and bacterial organisms
• Rapidly eliminates infection and relieves symptoms
• Kills organisms at tissue and intestinal levels
• Prevents infection complications and reinfection
• Affordable and widely available treatment

What Experts Say

Metronidazole is a nitroimidazole prodrug that undergoes reduction in anaerobic organisms to form reactive intermediates that damage microbial DNA. This mechanism makes it highly effective against protozoa and anaerobic bacteria while showing minimal activity against aerobic organisms. The selective toxicity derives from metabolic differences between host and pathogen cells.

Gastroenterologists recommend Flagyl for amebic dysentery, giardiasis, and anaerobic infections. It achieves excellent tissue penetration and is particularly effective for extraintestinal infections. Clinical improvement typically appears within 3 to 5 days for parasitic infections.

Take Flagyl with food or milk to minimize gastrointestinal upset. Complete the entire course regardless of symptom improvement to prevent relapse. Avoid alcohol during treatment and for 48 hours after completion.

Drug Class

• Nitroimidazole Antiparasitic and Antibiotic Agent

Packaging and Quantity

• Tablet 200 mg, 30 tablets per box (3 strips of 10)
• Tablet 400 mg, 30 tablets per box (3 strips of 10)

When Not to Use Flagyl

• Allergy to metronidazole or other nitroimidazoles
• First trimester of pregnancy without medical necessity
• Active blood dyscrasias or bone marrow disorders
• Severe liver disease or hepatic encephalopathy

Flagyl Tablet 400mg formula

• Metronidazole

Available forms

• Tablet
• Oral suspension
• Infusion

How to use Flagyl Tablet 400mg?

• Take as directed by your doctor, typically 200 to 400 mg three times daily
• Take with food or milk to minimize stomach upset
• Swallow tablet whole with a glass of water
• Take at regular intervals for consistent blood levels
• Complete the full course even if symptoms improve
• Avoid alcohol during treatment and 48 hours after completion

Drug Interactions

• Alcohol and alcohol-containing products: Causes disulfiram-like reaction. Avoid completely during and 48 hours after treatment.
• Warfarin and oral anticoagulants: May increase anticoagulant effects. Monitor INR closely.
• Lithium: May increase lithium levels. Monitor lithium concentration.

Risks and warnings

• Peripheral neuropathy: Rare risk with prolonged use. Report tingling or numbness immediately.
• Liver disease: Avoid or use with extreme caution in severe hepatic impairment.
• Blood dyscrasias: Risk of leukopenia. Monitor blood count with prolonged therapy.
• Pregnancy: Avoid first trimester if possible. Use only if benefits outweigh risks.

Flagyl Tablet Side Effects

Most side effects are mild and temporary:

• Metallic taste in mouth
• Nausea or vomiting
• Abdominal pain or cramping
• Diarrhea or constipation
• Headache or dizziness

Serious side effects require immediate medical attention:

• Severe allergic reaction: rash, swelling, difficulty breathing
• Severe nausea, vomiting, or abdominal pain
• Neurological symptoms: peripheral neuropathy, confusion
• Dark or bloody urine

Storage Conditions

• Store below 30 degrees Celsius in a cool, dry place
• Keep away from direct light and moisture
• Keep in original blister or container
• Do not store in bathroom or kitchen
• Keep out of reach of children
• Do not use after expiration date