Acefen Tablet 100mg

About Acefen Tablet 100mg

Acefen Tablet 100mg Uses

• Osteoarthritis pain and stiffness
• Rheumatoid arthritis
• Ankylosing spondylitis
• Postoperative pain
• Dental pain and toothache
• Muscle and joint sprains

Acefen Tablet 100mg Benefits

• Reduces joint swelling and stiffness
• Eases moderate to severe pain within an hour of dosing
• Improves mobility in chronic arthritis
• Better gastrointestinal tolerance than older NSAIDs

What Experts Say

Aceclofenac belongs to the phenylacetic acid class of nonsteroidal anti-inflammatory drugs, chemically related to diclofenac. It works by blocking cyclooxygenase enzymes, which reduces the production of prostaglandins responsible for pain, swelling, and stiffness in joint disease.

Clinical pharmacologists regard aceclofenac as a preferential COX-2 inhibitor. This means it tends to spare the stomach lining more than older NSAIDs at equivalent anti-inflammatory doses, which is why many rheumatologists favor it for patients who need regular pain control for arthritis or spinal conditions.

Long-term NSAID therapy still carries known cardiovascular and kidney risks regardless of the specific molecule chosen. Physicians generally recommend the lowest effective dose for the shortest necessary duration, along with periodic blood pressure and kidney function monitoring during extended treatment.

Drug Class

• Nonsteroidal Anti-Inflammatory Drug (NSAID)
• Phenylacetic Acid Derivative

Acefen Tablet 100mg formula

• Aceclofenac

Available forms

• Tablet

How to use Acefen Tablet 100mg?

• Take one tablet twice daily after meals, or as directed by the doctor.
• Swallow the tablet whole with a full glass of water.
• Do not crush or chew the tablet.
• Take at the same times each day for consistent pain relief.
• Do not exceed the dose prescribed by the doctor.

Drug Interactions

• Warfarin and other anticoagulants: Increases the risk of bleeding when combined with aceclofenac.
• Other NSAIDs and aspirin: Combining raises the risk of stomach ulcers and bleeding.
• ACE inhibitors and diuretics: Aceclofenac can reduce their blood pressure lowering effect and strain the kidneys.
• Lithium and methotrexate: Aceclofenac can raise blood levels of both drugs, increasing toxicity risk.
• Corticosteroids: Combined use further increases the risk of gastrointestinal ulceration.

Risks and warnings

• Heart disease: Use with caution in patients with a history of heart attack, stroke, or heart failure.
• Kidney disease: Avoid or use only under medical supervision in people with reduced kidney function.
• Pregnancy: Avoid in the third trimester due to risk of premature closure of the fetal ductus arteriosus.
• Peptic ulcer: Not recommended in patients with active or past stomach ulcers or gastrointestinal bleeding.
• Elderly patients: Higher risk of gastrointestinal and kidney side effects, requiring lower doses and closer monitoring.

Acefen Tablet 100mg Side Effects

• Stomach upset or indigestion
• Nausea
• Diarrhea
• Headache
• Dizziness
• Skin rash
• Fluid retention or swelling in ankles
• Raised liver enzymes
• Stomach ulcer or bleeding with prolonged use

Storage Conditions

• Store below 30°C in a cool, dry place away from direct sunlight.
• Keep the blister strip inside its original carton until use.
• Keep out of reach of children.
• Protect from moisture and humidity.
• Discard any tablets past the printed expiry date.