Acenac Injection 150mg

About Acenac Injection 150mg

Acenac Injection 150mg Uses

• Osteoarthritis pain and joint stiffness
• Rheumatoid arthritis flare ups
• Ankylosing spondylitis (spinal arthritis)
• Acute post operative pain
• Severe musculoskeletal pain, sprains and strains
• Acute low back pain

Acenac Injection 150mg Benefits

• Delivers pain relief faster than oral tablets since it bypasses the digestive tract
• Useful for patients who cannot swallow tablets or are nil by mouth after surgery
• Reduces joint swelling and stiffness, helping restore mobility sooner
• Single intramuscular dose can control acute pain until oral therapy is possible

What Experts Say

Aceclofenac is a phenylacetic acid derivative NSAID that blocks cyclooxygenase enzymes, lowering prostaglandin production at the site of tissue injury. The injectable form gives clinicians a faster and more reliable route when a patient cannot swallow tablets, is nil by mouth after surgery, or needs quicker pain control than an oral dose can provide.

Doctors in Pakistan commonly reach for a short course of Acenac Injection 150mg after orthopedic or general surgery, or during an acute flare of osteoarthritis and rheumatoid arthritis where oral absorption is unreliable. The deep intramuscular route bypasses first pass metabolism, so pain relief and reduced joint swelling often begin within thirty to sixty minutes.

NSAID injections carry a higher gastrointestinal, renal and cardiovascular risk than oral tablets, so most physicians limit use to one or two days before switching the patient to an oral aceclofenac formulation. Renal function and blood pressure are usually checked first in patients with kidney disease, uncontrolled hypertension or heart failure, since these conditions raise the chance of fluid retention with any NSAID.

Drug Class

• Non Steroidal Anti Inflammatory Drug (NSAID)
• Phenylacetic acid derivative
• Non selective cyclooxygenase (COX 1 and COX 2) inhibitor

Acenac Injection 150mg formula

• Aceclofenac

Available forms

• Injection

How to use Acenac Injection 150mg?

• Give Acenac Injection 150mg by deep intramuscular injection into the gluteal region only
• The usual adult dose is one 150mg ampule once daily
• Use for the shortest duration needed, generally one to two days, before switching to oral aceclofenac
• Do not administer through the intravenous route
• Allow a trained healthcare worker to give the injection, not for self administration
• Inform the doctor about kidney, liver or heart conditions before the injection is given

Drug Interactions

• Anticoagulants (warfarin): Increases the risk of bleeding when combined with Acenac Injection 150mg
• Other NSAIDs and aspirin: Raises the risk of stomach ulcers and gastrointestinal bleeding when used together
• ACE inhibitors and ARBs: Can reduce blood pressure control and increase the risk of kidney injury
• Diuretics: Effectiveness may be reduced and the risk of kidney impairment increases
• Lithium: Aceclofenac can raise lithium blood levels, increasing the risk of toxicity
• Methotrexate: Aceclofenac can raise methotrexate levels and increase its toxicity
• Corticosteroids: Combined use raises the risk of gastrointestinal ulcers and bleeding

Risks and warnings

• Gastrointestinal risk: Can cause stomach pain, ulcers or bleeding, especially with long term or repeated use
• Cardiovascular risk: May raise the chance of heart attack or stroke, particularly in patients with existing heart disease or high blood pressure
• Renal risk: Can reduce kidney blood flow and worsen kidney function in patients who are dehydrated or have existing kidney disease
• Injection site reaction: Pain, redness, swelling or a hard lump can develop at the injection site
• Hepatic risk: May raise liver enzymes, monitor in patients with existing liver disease
• Hypersensitivity: Avoid in patients with a known allergy to aceclofenac, aspirin or other NSAIDs, including those with asthma triggered by NSAIDs

Acenac Injection 150mg Side Effects

• Pain, redness or swelling at the injection site
• Nausea and stomach discomfort
• Indigestion or heartburn
• Diarrhea or loss of appetite
• Headache and dizziness
• Skin rash or itching
• Stomach ulcers or gastrointestinal bleeding
• Yellowing of the eyes or skin
• Swelling of the face, lips or throat
• Sudden shortness of breath or chest pain

Storage Conditions

• Store below 30 degrees Celsius in a cool, dry place
• Protect ampules from direct light
• Do not freeze
• Keep out of reach of children
• Use the ampule immediately after opening and discard any unused portion
• Check the ampule for particles or discoloration before use