Albrotran Tablet 80mg / 400mg

About Albrotran Tablet 80mg / 400mg

Uses

• Urinary tract infections caused by susceptible bacteria
• Certain respiratory tract infections such as bronchitis flare ups
• Traveler's diarrhea caused by bacterial infection
• Ear infections in some cases
• Pneumocystis pneumonia prevention or treatment in specific patients, as directed by a doctor

Benefits

• Combines two antibiotics that work together against a broad range of bacteria
• Affordable option widely available across Pakistan
• Oral tablet form that avoids the need for injections in most cases

What Experts Say

Doctors across Pakistan prescribe this combination for uncomplicated urinary tract infections, a condition that remains common in women during hot summer months due to dehydration. Clinics in Lahore, Karachi, Islamabad and Rawalpindi report a steady rise in such cases during peak summer heat.

Pharmacology texts describe this pairing as working through two separate steps in bacterial folate production, which is why the combination is often more effective than either drug alone. Blocking both steps together also lowers the chance of bacteria developing resistance to just one drug.

Guidelines from infectious disease specialists stress finishing the complete course even after symptoms improve. Stopping early is a leading reason resistant bacteria develop, making future infections harder to treat. A repeat urine test is sometimes advised if symptoms persist after the course ends.

Drug Class

• Sulfonamide antibiotic combination

Albrotran Tablet 80mg / 400mg formula

• Trimethoprim + Sulfamethoxazole

Available forms

• Tablet

How to use Albrotran Tablet 80mg / 400mg?

• Take exactly as prescribed by your doctor, usually every 12 hours
• Swallow the tablet with a full glass of water
• Drink plenty of fluids while taking this medicine
• Complete the full course even if you feel better early
• Take with food if it upsets your stomach

Drug Interactions

• Warfarin: Can increase bleeding risk by boosting warfarin's effect
• Methotrexate: May raise methotrexate levels and toxicity risk
• ACE inhibitors or potassium sparing diuretics: Can raise blood potassium levels
• Oral diabetes medicines: May increase the blood sugar lowering effect

Risks and warnings

• Sulfa allergy: Avoid if you have had a reaction to sulfa drugs before
• Kidney or liver disease: Needs dose adjustment and close monitoring
• Pregnancy: Generally avoided, especially in the first trimester and near delivery
• Blood disorders: Use with caution in people with G6PD deficiency or low blood counts
• Skin reactions: Stop the medicine and seek care if a rash, blistering or peeling skin develops

Albrotran Tablet 80mg / 400mg Side Effects

• Nausea or vomiting
• Loss of appetite
• Diarrhea
• Skin rash
• Headache
• Sensitivity to sunlight
• Dizziness
• Rarely, severe allergic reactions

Storage Conditions

• Store below 25°C in a dry place
• Protect from light and moisture
• Keep out of reach of children
• Discard any leftover tablets after finishing treatment as advised by your pharmacist