Amphyll Injection 250mg

About Amphyll Injection 250mg

Uses

• Acute severe asthma attacks
• COPD exacerbations
• Bronchospasm
• Emergency relief of breathlessness

Benefits

• Rapid relief of airway narrowing during a severe attack
• Useful add on treatment when inhalers alone are not enough

What Experts Say

Pulmonologists reserve aminophylline mainly for severe asthma or COPD flare ups that do not respond fully to standard inhalers, since it works through a different pathway to relax the airway muscles and ease breathing during an emergency.

Doctors are careful with dosing because aminophylline has a narrow safety margin, meaning the difference between an effective dose and a toxic one is small. Blood level monitoring is often recommended, especially with repeated or prolonged use in a hospital setting.

Specialists also caution that common substances like caffeine and certain antibiotics can raise aminophylline levels in the blood, increasing the risk of side effects such as a racing heart or tremors. This is why treatment is closely supervised by medical staff. Emergency physicians add that this injection is usually kept for situations where breathing difficulty is severe enough to need hospital level care, rather than for routine or mild asthma symptoms managed at home with inhalers.

Drug Class

• Xanthine bronchodilator

Amphyll Injection 250mg formula

• Aminophylline

Available forms

• Injection

How to use Amphyll Injection 250mg?

• Given as a slow intravenous injection or infusion by a healthcare professional
• Usually administered in a hospital or emergency setting
• Dose is calculated based on body weight and response

Drug Interactions

• Ciprofloxacin And Other Fluoroquinolones: Raise aminophylline levels
• Cimetidine: Raises aminophylline levels
• Erythromycin And Clarithromycin: Raise aminophylline levels
• Phenytoin And Rifampin: Lower aminophylline levels
• Caffeine And Other Stimulants: Increased risk of side effects

Risks and warnings

• Narrow Safety Margin: Requires close monitoring of blood levels
• Heart Disease: Use with caution
• Thyroid Disorders: Use with caution
• Peptic Ulcer And Seizure Disorders: Use with caution
• Current Medicines: Inform your doctor about all medicines you are taking

Side Effects

• Nausea and vomiting
• Headache
• Restlessness
• Fast heartbeat
• Irregular heart rhythm at high doses
• Seizures (rare, usually from toxic levels)
• Severe drop in blood pressure (rare)

Storage Conditions

• Store below 25°C and protect from light
• Do not use if the solution looks discolored or cloudy
• Keep out of reach of children