Ampress Tablet 5mg

About Ampress Tablet 5mg

Ampress Tablet 5mg Uses

• High blood pressure (hypertension)
• Chronic stable angina (chest pain)
• Vasospastic (Prinzmetal's) angina
• Coronary artery disease, to reduce the risk of hospitalization

Ampress Tablet 5mg Benefits

• Once daily dosing with smooth, long lasting blood pressure control
• Reduces the frequency of angina attacks by relaxing coronary blood vessels
• Can be safely combined with other blood pressure medicines for better control
• Does not require dose adjustment in most patients with kidney disease

Drug Class

• Calcium Channel Blocker (dihydropyridine)

What Experts Say

Amlodipine Besylate blocks calcium channels in the smooth muscle of blood vessel walls, preventing calcium from entering these cells. This relaxes and widens blood vessels, lowering the resistance the heart pumps against. The same effect improves blood flow to the heart muscle, relieving angina by increasing oxygen supply.

Its long elimination half-life of roughly 30 to 50 hours allows steady, once daily dosing without sharp peaks and troughs in blood pressure control, making it a first-line option for long term hypertension management. This gradual onset means it takes about a week of regular use before the full effect is seen.

Ankle swelling is the most common side effect and results directly from the drug's effect on small blood vessels, not fluid retention by the kidneys, so it does not typically respond to diuretics. Doctors usually start at a low dose and increase gradually to reduce swelling and reflex increases in heart rate.

Ampress Tablet 5mg formula

• Amlodipine Besylate

Available forms

• Tablet

How to use Ampress Tablet 5mg?

• Take one tablet once daily, with or without food
• Swallow the tablet whole with water, at the same time each day
• Do not stop taking suddenly without consulting your doctor
• If a dose is missed, take it as soon as remembered unless it is nearly time for the next dose

Drug Interactions

• Simvastatin: Increases simvastatin levels in the blood, raising the risk of muscle related side effects, so dose limits apply
• CYP3A4 Inhibitors: Medicines like ketoconazole or certain antibiotics can raise Amlodipine levels in the blood
• Other Blood Pressure Medicines: Combined use can lead to an excessive drop in blood pressure
• Grapefruit Juice: May increase Amlodipine levels and the risk of side effects

Risks and warnings

• Low Blood Pressure: Can cause a marked drop in blood pressure, especially when starting treatment or increasing the dose
• Liver Impairment: Patients with liver disease may need a lower starting dose since the drug is processed by the liver
• Severe Aortic Stenosis: Should be used with caution in patients with this heart valve condition
• Worsening Angina: Rarely, some patients may experience increased chest pain shortly after starting treatment, particularly with severe coronary artery disease

Ampress Tablet 5mg Side Effects

• Swelling of the ankles or feet
• Headache
• Flushing
• Dizziness
• Fatigue
• Palpitations
• Nausea
• Excessive drowsiness or low blood pressure with overdose

Storage Conditions

• Store below 30°C in a cool, dry place away from direct sunlight
• Keep the tablets in their original blister pack until ready to use
• Keep out of reach of children
• Do not use after the expiry date printed on the pack