About Androcur Tablet 50mg
Androcur Tablet 50mg contains Cyproterone Acetate, a steroidal antiandrogen used in prostate cancer therapy.
Androcur Tablet 50mg Uses
- Advanced prostate cancer, to reduce testosterone driven tumour growth
- Severe hirsutism (excess facial and body hair) in women
- Severe acne and seborrhoea linked to high androgen levels
- Androgenetic hair loss in women in select cases
- Precocious puberty in specific hormonal disorders
- Reduction of sexual drive in cases of hypersexuality under specialist care
Androcur Tablet 50mg Benefits
- Slows tumour growth by blocking testosterone action on prostate cancer cells
- Reduces excess androgen driven hair growth and acne over months of regular use
- Helps regulate hormonal imbalance in select endocrine conditions
- A well established antiandrogen with decades of clinical use behind it
What Experts Say
Doctors prescribe Cyproterone Acetate cautiously because its antiandrogen effect depends on steady dosing and regular monitoring. Physicians typically start at the lowest effective dose and review liver function tests before and during treatment, since the drug carries a recognised risk of hepatotoxicity.
Specialists weigh the cumulative dose carefully in long term use, since sustained high doses have been linked to a higher chance of benign brain tumours called meningiomas. Many endocrinologists now prefer the lowest dose that controls symptoms and reassess treatment duration at regular intervals.
Physicians also monitor for adrenal insufficiency risk if the medicine is stopped abruptly after prolonged use, since the body's own hormone production can be suppressed. Doctors generally combine Cyproterone Acetate therapy with periodic blood pressure and mood assessments, given its known effects on cardiovascular risk and emotional wellbeing.
Drug Class
- Steroidal Antiandrogen
- Progestogen (Antigonadotropic Agent)
Androcur Tablet 50mg Uses in Urdu
- پروسٹیٹ کینسر میں ٹیسٹوسٹیرون کی سطح کم کرنے کے لیے استعمال ہوتی ہے۔
- خواتین میں زیادہ بالوں کی بڑھوتری یعنی ہرسوٹزم کے علاج میں مددگار ہے۔
- شدید مہاسوں اور ہارمونل مسائل پر قابو پانے کے لیے تجویز کی جاتی ہے۔
- خواتین میں بالوں کے گرنے کے بعض کیسز میں استعمال کی جاتی ہے۔
- ہارمونل عدم توازن کو ٹھیک کرنے میں مدد دیتی ہے۔
Androcur Tablet 50mg formula
How to use Androcur Tablet 50mg?
- Take Androcur Tablet 50mg exactly as prescribed by a specialist, usually once or twice daily with food.
- Swallow the tablet whole with a full glass of water.
- Do not stop the medicine suddenly without consulting the prescribing doctor.
- Attend every scheduled liver function and blood test throughout treatment.
- Report any new headache, vision change or breathing difficulty right away.
Drug Interactions
- Ketoconazole and Strong CYP3A4 Inhibitors: These drugs raise Cyproterone Acetate blood levels and increase the risk of side effects.
- Rifampicin, Phenytoin and Other CYP3A4 Inducers: These can lower Cyproterone Acetate levels by up to eightfold, reducing its effectiveness.
- Corticosteroids: Combined use may increase the risk of adrenal suppression and fluid retention.
- Anticoagulants: Cyproterone Acetate can alter clotting risk, so dose adjustment may be needed with blood thinners.
- Insulin and Oral Hypoglycemics: The medicine can affect blood sugar control, requiring closer glucose monitoring.
Risks and warnings
- Hepatotoxicity: Cyproterone Acetate can cause liver enzyme elevation, hepatitis or rare liver failure, so liver function tests are checked before and during therapy.
- Meningioma Risk: Long term use, especially at higher cumulative doses, is linked to a greater chance of developing benign brain tumours called meningiomas.
- Adrenal Suppression: The medicine can suppress the body's natural cortisol production, so it should never be stopped abruptly without medical guidance.
- Thromboembolism: The drug raises the risk of blood clots in the legs or lungs, particularly in smokers and people with a history of clotting disorders.
- Cardiovascular Risk: Use with caution in patients with heart disease, since fluid retention and lipid changes can occur.
- Pregnancy and Breastfeeding: Strictly contraindicated, since the drug can cause feminisation of a male fetus and passes into breast milk.
- Diabetes: Cyproterone Acetate can affect glucose tolerance, so blood sugar should be monitored in diabetic patients.
Androcur Tablet 50mg Side Effects
- Hot flushes and excessive sweating
- Fatigue and low energy
- Weight gain
- Reduced libido and erectile changes in men
- Breast tenderness or gynecomastia in men
- Mood changes, irritability or depression
- Menstrual irregularities in women
- Liver enzyme changes or jaundice, a signal for urgent review
- Shortness of breath or leg swelling suggesting a blood clot
- Persistent headache, vision changes or seizures, possible meningioma warning signs
- Adrenal insufficiency symptoms such as severe weakness or dizziness after stopping treatment
Storage Conditions
- Store below 30°C in a cool, dry place away from direct sunlight.
- Keep the tablets in their original blister strip until ready to use.
- Keep out of reach of children and pets.
- Do not store in the bathroom or near a sink due to moisture exposure.
- Discard any expired or discoloured tablets safely.
