About Anplag Tablet 60 mg
Anplag Tablet 60 mg is a ticagrelor antiplatelet used to prevent heart attack and stroke after ACS.
Anplag Tablet 60 mg Uses
- Prevention of heart attack in people with acute coronary syndrome (ACS)
- Prevention of stroke in people at high risk of blood clots
- Used with aspirin after a stent procedure to prevent clot formation inside the stent
- Reduces the risk of cardiovascular death in people with coronary artery disease
Anplag Tablet 60 mg Benefits
- Lowers the chance of a second heart attack after ACS
- Acts faster and more predictably than older antiplatelet drugs like clopidogrel
- Reduces the risk of stent blockage after angioplasty
- Helps protect narrowed or damaged coronary arteries from further blockage
What Experts Say
Ticagrelor works by reversibly blocking the P2Y12 receptor on platelets. This stops platelets from clumping together and forming clots inside narrowed or damaged coronary arteries. Unlike clopidogrel, it does not need liver activation to become active, and its antiplatelet effect wears off faster once the tablet is stopped, which matters before surgery.
Large clinical trials in patients with acute coronary syndrome showed that ticagrelor lowered the combined risk of cardiovascular death, heart attack, and stroke compared with older antiplatelet drugs. It is usually paired with a low dose of aspirin, since aspirin doses above 100 mg can actually reduce how well ticagrelor works in the body.
The main safety concern with this class of medicine is bleeding, since it interferes with the body's normal clotting response. Some patients notice breathlessness in the first weeks of treatment, which is usually harmless but should still be reported to a doctor. Physicians also monitor heart rhythm, since stopping the medicine early without medical advice raises the risk of a repeat heart attack.
Drug Class
- Antiplatelet agent
- P2Y12 receptor inhibitor
- Cyclopentyltriazolopyrimidine (CPTP) class antithrombotic
Anplag Tablet 60 mg Uses in Urdu
- دل کے دورے سے بچاؤ کے لیے استعمال ہوتی ہے
- فالج کا خطرہ کم کرنے میں مددگار ہے
- انجیوپلاسٹی یا اسٹینٹ لگنے کے بعد خون کے لوتھڑے بننے سے روکتی ہے
- دل کی شریانوں میں خون کی روانی بہتر رکھنے میں مدد دیتی ہے
Anplag Tablet 60 mg formula
How to use Anplag Tablet 60 mg?
- Take Anplag Tablet 60 mg exactly as prescribed by your cardiologist.
- Usually taken twice daily, with or without food.
- Take with a full glass of water.
- Take doses at the same times each day to keep a steady level in the blood.
- Continue taking low dose aspirin alongside this medicine unless your doctor says otherwise.
- Do not stop this medicine before dental work or surgery without consulting your doctor first.
- If a dose is missed, take it as soon as remembered, but skip it if the next dose is almost due.
Drug Interactions
- Aspirin (high dose): Maintenance doses above 100 mg daily reduce how well ticagrelor works and should be avoided.
- Strong CYP3A4 inhibitors: Drugs like ketoconazole, clarithromycin, and ritonavir raise ticagrelor levels and bleeding risk.
- Strong CYP3A4 inducers: Drugs like rifampin, phenytoin, and carbamazepine lower ticagrelor levels and reduce its effect.
- Simvastatin or lovastatin: Doses above 40 mg daily should be avoided when taken with ticagrelor.
- Anticoagulants: Warfarin and heparin increase the combined risk of serious bleeding.
- NSAIDs: Regular use of drugs like ibuprofen or diclofenac increases bleeding risk.
- Opioids: Morphine and similar painkillers can delay and reduce absorption of ticagrelor.
Risks and warnings
- Bleeding risk: Can cause serious, and rarely fatal, bleeding, including in the brain.
- Active bleeding: Should not be used in people with active pathological bleeding or a history of bleeding inside the brain.
- Do not stop suddenly: Stopping this medicine early without medical advice raises the risk of heart attack and stent blockage.
- Before surgery: Needs to be paused several days before planned surgery, only under a doctor's guidance.
- Breathing difficulty: Shortness of breath is common in early treatment. Report if it is severe or does not improve.
- Liver impairment: Should be avoided in people with severe liver disease.
- Heart rhythm disorders: Use with caution in people with a history of slow or irregular heartbeat.
- Pregnancy and breastfeeding: Use only if clearly advised by a doctor, since safety data in these groups is limited.
Anplag Tablet 60 mg Side Effects
- Shortness of breath (dyspnea)
- Easy bruising
- Minor bleeding from gums or nose
- Dizziness
- Headache
- Nausea
- Diarrhea
- Fatigue
- Severe or uncontrolled bleeding
- Blood in urine or stool
- Coughing up blood
- Sudden weakness, confusion, or difficulty speaking, which can signal a stroke
- Slow or irregular heartbeat
Storage Conditions
- Store at room temperature between 20°C and 25°C.
- Keep tablets in their original blister pack until ready to use.
- Protect from moisture and direct sunlight.
- Keep out of reach of children.
- Dispose of unused or expired tablets safely, not in household trash.
