Bacticef Injection 500mg / 500mg

About Bacticef Injection 500mg / 500mg

Bacticef Injection Uses

• Treats severe respiratory tract infections
• Treats complicated urinary tract infections
• Used for intra-abdominal infections like peritonitis
• Treats skin and soft tissue infections
• Used for septicemia caused by susceptible bacteria

Bacticef Injection Benefits

• Combines an antibiotic with a beta-lactamase inhibitor for stronger action
• Effective against bacteria resistant to plain cephalosporins
• Used in hospitals for moderate to severe infections
• Broad spectrum coverage against many resistant bacteria

What Experts Say

Serious bacterial infections needing hospital-level antibiotics are common in Pakistani hospitals, particularly for pneumonia, complicated urinary infections and abdominal infections. Bacticef Injection combines cefoperazone, a broad-spectrum cephalosporin, with sulbactam, which blocks the enzyme many bacteria use to resist antibiotics.

This combination allows the antibiotic to work against bacteria that would otherwise survive treatment with cefoperazone alone. It is given directly into a vein or muscle by a trained healthcare provider, usually every 12 hours depending on the severity of the infection.

Patients should tell their doctor about any past penicillin or cephalosporin allergy before receiving this injection, since severe allergic reactions are possible. This medicine is only given under medical supervision and is not meant for self-administration at home.

Drug Class

• Cephalosporin and Beta-Lactamase Inhibitor Combination
• Antibiotic

Bacticef Injection 500mg / 500mg formula

• Cefoperazone + Sulbactam

Available forms

• Injection

How to use Bacticef Injection 500mg / 500mg?

• Administered by injection into a vein or muscle by a healthcare professional
• Usual adult dose is 1 to 2 grams every 12 hours, adjusted to infection severity
• Given only in a hospital or clinical setting
• Dose and duration are set by the treating doctor based on response

Drug Interactions

• Alcohol: Can cause a disulfiram-like reaction with flushing and nausea
• Anticoagulants like Warfarin: May increase bleeding risk
• Aminoglycoside Antibiotics: Combined use raises the risk of kidney effects
• Probenecid: May increase cefoperazone blood levels

Risks and warnings

• Avoid in patients with known penicillin or cephalosporin allergy
• Use with caution in patients with liver or kidney impairment
• Not recommended during pregnancy unless clearly necessary
• Monitor closely for signs of allergic reaction during administration

Bacticef Injection 500mg / 500mg Side Effects

• Pain or swelling at the injection site
• Diarrhea
• Nausea and vomiting
• Skin rash
• Abnormal liver enzyme levels in some patients

Storage Conditions

• Store below 25°C in a cool, dry place away from light
• Use reconstituted solution promptly as directed by the manufacturer
• Keep out of reach of children
• Do not use after the expiry date