CLA tablet 250mg / 125mg

About CLA tablet 250mg / 125mg

CLA Tablet Uses

• Respiratory infections such as bronchitis, pneumonia, and sinusitis.
• Ear, nose, and throat infections including tonsillitis and otitis media.
• Urinary tract infections caused by susceptible bacteria.
• Skin and soft tissue infections including cellulitis and wound infections.
• Dental infections and abscesses.
• Bone and joint infections in certain cases.

CLA Tablet Benefits

• Beta-lactamase inhibitor component overcomes common resistance mechanisms.
• Broader bacterial coverage compared to amoxicillin alone.
• Effective option for mixed or polymicrobial infections.
• Well established safety profile with decades of clinical use.

What Experts Say

This combination pairs amoxicillin with clavulanic acid, a beta-lactamase inhibitor. Clavulanic acid blocks the enzyme many resistant bacteria use to break down amoxicillin. This allows the combination to work against a wider range of organisms compared to amoxicillin alone.

Clinicians generally reserve this combination for infections where resistant or mixed bacteria are suspected, rather than using it as a first choice for every infection. Completing the full prescribed course matters even if symptoms improve early. Stopping treatment too soon can allow surviving bacteria to develop further resistance.

Gastrointestinal upset is the most frequently reported issue, often linked to the clavulanic acid component rather than amoxicillin itself. A known penicillin allergy is a reason to avoid this medicine entirely. Liver function is occasionally monitored during longer courses, since rare cases of drug related liver changes have been documented with this combination.

Drug Class

• Penicillin-type antibiotic combined with a beta-lactamase inhibitor (aminopenicillin plus clavulanate).

CLA tablet 250mg / 125mg formula

• Amoxicillin + Clavulanic Acid

Available forms

• Tablet

How to use CLA tablet 250mg / 125mg?

• The tablet should be swallowed whole with a glass of water.
• Taking it with food can reduce stomach upset.
• Doses should be spaced evenly through the day as directed by the doctor.
• The full course should be completed even if symptoms improve early.
• Irregular use lowers effectiveness, so doses should not be skipped.

Drug Interactions

• Methotrexate: Increased risk of methotrexate toxicity when combined with this antibiotic.
• Allopurinol: Higher chance of skin rash when taken alongside this combination.
• Warfarin And Other Blood Thinners: Bleeding risk may increase, so clotting levels should be monitored closely.
• Oral Contraceptives: Effectiveness of hormonal birth control may be reduced during treatment.
• Probenecid: Can raise blood levels of amoxicillin by slowing its removal from the body.

Risks and warnings

• Penicillin Allergy: A history of allergic reaction to penicillin or cephalosporin antibiotics is a reason to avoid this medicine.
• Liver Function: Rare cases of liver related side effects have been linked to this combination, more common with longer or repeated courses.
• Kidney Impairment: Dose adjustment is often needed in people with reduced kidney function.
• Pregnancy And Breastfeeding: Use only under medical supervision, since safety should be reviewed by a doctor first.
• Incomplete Course: Stopping the medicine early can allow the infection to return and contributes to antibiotic resistance.

CLA Tablet Side Effects

• Nausea or stomach discomfort
• Diarrhea
• Vomiting
• Skin rash
• Headache
• Vaginal itching or discharge in some women
• Severe allergic reaction with swelling or difficulty breathing (rare)
• Signs of liver problems such as yellowing of the skin or eyes (rare)

Storage Conditions

• Store below 25°C in a cool, dry place away from direct sunlight.
• Keep the strip in its original packaging until the dose is due.
• Keep out of reach of children.
• Do not use the tablet after the expiry date printed on the pack.
• Avoid storing in the bathroom or near a kitchen sink where moisture is high.