Clamoxin DS Tablet 500mg / 125mg

About Clamoxin DS Tablet 500mg / 125mg

Clamoxin DS Tablet Uses

• Respiratory tract infections such as sinusitis and bronchitis
• Ear infections including otitis media
• Urinary tract infections
• Skin and soft tissue infections
• Dental and gum infections

Clamoxin DS Tablet Benefits

• Clears bacterial infections that resist plain amoxicillin
• Clavulanic acid protects amoxicillin from bacterial enzymes
• Broad coverage against common respiratory and skin pathogens
• Convenient twice daily dosing for most infections

What Experts Say

Physicians in Pakistan frequently prescribe amoxicillin with clavulanic acid when a plain amoxicillin course has already failed or when the infecting organism produces beta lactamase enzymes. The clavulanic acid component blocks this enzyme, restoring amoxicillin's ability to kill the bacteria.

This combination is considered a reliable option for recurrent sinusitis, otitis media and complicated urinary tract infections in general practice. Doctors weigh the higher risk of diarrhea against the broader bacterial coverage this combination provides compared to amoxicillin alone.

Culture and sensitivity testing is recommended for infections that do not respond within 48 to 72 hours. Clinicians also monitor liver enzymes during prolonged use, since amoxicillin clavulanate carries a small but recognized risk of cholestatic liver injury, particularly in older adults.

Drug Class

• Beta lactam antibiotic combined with a beta lactamase inhibitor

Clamoxin DS Tablet 500mg / 125mg formula

• Amoxicillin + Clavulanic Acid

Available forms

• Tablet

How to use Clamoxin DS Tablet 500mg / 125mg?

• Take this tablet with a meal to reduce stomach upset.
• Swallow the tablet whole with a full glass of water.
• Complete the full course even if symptoms improve early.
• Take doses at evenly spaced intervals as advised by your doctor.

Drug Interactions

• Methotrexate: Amoxicillin can raise methotrexate levels and increase toxicity risk.
• Allopurinol: Combined use increases the chance of skin rash.
• Oral Contraceptives: May reduce the reliability of hormonal birth control pills.
• Warfarin: Can enhance the blood thinning effect and raise bleeding risk.
• Probenecid: Slows amoxicillin elimination and raises blood levels.

Risks and warnings

• Penicillin Allergy: Avoid if you have had an allergic reaction to penicillin or cephalosporin antibiotics.
• Liver Function: Use with caution in patients with a history of liver problems linked to amoxicillin clavulanate.
• Kidney Impairment: Dose adjustment is needed in patients with reduced kidney function.
• Pregnancy and Breastfeeding: Use only if clearly needed and advised by a doctor.

Clamoxin DS Tablet Side Effects

• Diarrhea and loose stools
• Nausea and vomiting
• Skin rash or itching
• Vaginal itching or discharge (yeast infection)
• Abdominal discomfort
• Headache
• Severe allergic reaction with swelling and difficulty breathing (rare)
• Yellowing of skin or eyes indicating liver problems (rare)
• Severe watery or bloody diarrhea suggesting colitis (rare)

Storage Conditions

• Store at room temperature below 25°C.
• Keep in the original blister pack away from moisture.
• Protect from direct sunlight and heat.
• Keep out of reach of children.