Diabold Plus Tablet 2mg / 500mg

About Diabold Plus Tablet 2mg / 500mg

Diabold Plus Tablet 2mg / 500mg Uses

• Type 2 diabetes mellitus when a single oral drug is not enough
• Blood sugar control alongside diet and exercise
• Combination therapy replacing two separate tablets

Diabold Plus Tablet 2mg / 500mg Benefits

• Blood sugar is targeted through two complementary mechanisms
• A lower total number of daily tablets needed
• More consistent long term blood sugar control
• Widely used, well studied combination for type 2 diabetes

What Experts Say

Glimepiride stimulates the pancreas to release more insulin, while metformin reduces how much glucose the liver produces and helps tissues respond better to the insulin already present. Combining the two in one tablet targets blood sugar from two different directions, which is why the combination often works better than either drug alone at matched doses.

Type 2 diabetes is extremely common in Pakistan, and many patients need more than one mechanism to reach their target blood sugar once diet, exercise, and a single oral drug are no longer enough. A fixed dose combination tablet also simplifies the daily pill count, which research consistently links to better long term adherence and more stable control.

Kidney function is checked before starting, since metformin needs to be avoided or reduced when kidney function drops, and glimepiride's hypoglycemia risk rises further in that setting. Patients are counseled to never skip a meal after this tablet, since the glimepiride component works regardless, and doctors watch for early low blood sugar signs such as sweating or shakiness.

Drug Class

• Sulfonylurea and Biguanide Combination (Oral Antidiabetic)

Diabold Plus Tablet 2mg / 500mg formula

• Glimepiride + Metformin Hydrochloride

Available forms

• Tablet

How to use Diabold Plus Tablet 2mg / 500mg?

• This tablet is usually taken once daily with breakfast or the first main meal.
• A skipped meal after this tablet raises the risk of low blood sugar.
• Regular blood sugar checks help track how well this tablet is working.
• Plenty of water with this tablet supports the metformin component's absorption.

Drug Interactions

• Insulin or other diabetes medicines: Combined use raises the risk of low blood sugar.
• Alcohol: The risk of both hypoglycemia and lactic acidosis rises with regular alcohol use.
• Iodinated contrast dye: This tablet is usually paused before and after imaging procedures using contrast dye.
• Corticosteroids: Can raise blood sugar and reduce how well this tablet works.

Risks and warnings

• Hypoglycemia: Low blood sugar risk is higher with this tablet, especially if a meal is skipped after dosing.
• Lactic acidosis: A rare but serious metformin related risk that increases with kidney or liver impairment.
• Kidney function: This tablet is not recommended when kidney function is significantly reduced.
• Alcohol: Regular alcohol use raises the risk of both hypoglycemia and lactic acidosis.
• Surgery or contrast dye procedures: This tablet is usually paused around major surgery or imaging that uses iodine contrast dye.

Diabold Plus Tablet 2mg / 500mg Side Effects

• Nausea
• Diarrhea
• Stomach upset
• Low blood sugar (hypoglycemia)
• Metallic taste
• Loss of appetite
• Vitamin B12 deficiency with long term use

Storage Conditions

• Store below 30°C in a cool, dry place away from sunlight.
• Keep the tablet in its original blister strip until use.
• Avoid storing in a humid bathroom cabinet.
• Keep out of reach of children.