Quick facts

  • Anaerobic infection/clostridium difficile infection
  • Pylori eradication
  • Fistulating Crohn's disease
  • Pelvic inflammatory disease
  • Surgical prophylaxis
  • Invasive intestinal amoebiasis
  • Extra-intestinal amoebiasis
  • Liver abscess
  • Urogenital trichomoniasis
  • Giardiasis
  • Intestinal amebiasis

Entamizole DS Tablet 500mg/400mg

by Abbott Laboratories

Entamizole DS is used to treat stomach and intestinal infections like amoebiasis and giardiasis.

Rs. 113.67
Rs. 113.67

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More info on this medicine

Table of contents

Entamizole DS Tablet Uses

Entamizole DS is a combination of metronidazole and diloxanide furoate. Metronidazole is an antibiotic and antiprotozoal drug that does not show any action against viral infections. It works by stopping the growth of bacteria or protozoa.

Moreover, diloxanide furoate is an antiprotozoal drug that helps eradicate protozoa in asymptomatic patients. It can be given alone. But most commonly, it is given in combination with metronidazole.

Entamizole DS is given in all age groups. From children to elders. If you have a complaint of stomach ache and diarrhea, your healthcare provider might prescribe it if they suspect you have a stomach infection.

Entamizole DS Tablet Uses in Urdu

Entamizole DS metronidazole اور diloxanide furoate کا ایک مجموعہ ہے۔ Metronidazole ایک اینٹی بائیوٹک اور antiprotozoal دوا ہے جو وائرل انفیکشن کے خلاف کوئی کارروائی نہیں دکھاتی ہے۔ یہ بیکٹیریا یا پروٹوزوا کی افزائش کو روک کر کام کرتا ہے۔ مزید برآں، diloxanide furoate ایک antiprotozoal دوا ہے جو غیر علامات والے مریضوں میں پروٹوزوا کو ختم کرنے میں مدد کرتی ہے۔ یہ اکیلے دیا جا سکتا ہے. لیکن عام طور پر، یہ میٹرو نیڈازول کے ساتھ مل کر دیا جاتا ہے۔

Entamizole DS Tablet 500mg/400mg formula

  • Diloxanide Furoate
  • Metronidazole

Available forms

  • Tablets

Risks and warnings

You should know the risks and warnings of Entamizole DS to prevent its misuse.

There are some specific circumstances under which the use of certain medications is contraindicated or considered dangerous. So if you are taking any medicine its always a good practice to familiarize yourself with its risks and warnings.

The risks and warnings associated with Entamizole DS are:

1. Pregnant or breastfeeding

Pregnant women should not take Entamizole DS unless advised otherwise by their doctor. Women who are breastfeeding should also consult their healthcare provider before taking Entamizole DS.

2. Allergic to Entamizole DS

If you are allergic to metronidazole or diloxanide furoate, do not take Entamizole DS or any other medicine with the same generic name. Allergies can be mild, but in certain cases, people may also have a severe reaction, known as anaphylactic shock. In this condition, the person is under an imminent threat of death, unless they are given immediate medical care or shot from an EpiPen. Thus, disclose all your allergies to your healthcare provider so that your medical history contains all pertinent information.

3. Non-susceptible Organisms

Entamizole DS should be given to the patient only when the organism is sensitive to it. If not, it can lead to antibiotic resistance, making it difficult to treat infections next time. Mostly, it applies to stomach infections.

4. Seizures

If you have a history of seizures or renal impairment, you must avoid Entamizole DS as it can provoke seizures. Also, if you have conditions that can cause seizures, like a brain tumor, brain injury, or cerebral atherosclerosis, you must take Entamizole DS with caution. Moreover, you must inform your healthcare provider about your complete health condition.

5. Kidney Failure

If your kidneys are not functioning well, your healthcare provider may prescribe milder drugs, or lower dosages, to not overwhelm your kidneys.

Our kidneys perform the vital task of removing toxins and waste products from the body. However, when kidneys are malfunctioning, naturally, their output is decreased i.e., less waste is removed from the body. Thus, patients should put less load on the kidney, as otherwise, the toxins accumulate in the body, which hurts the health of the person. Therefore if you have kidney disease, you should only take Entamizole DS with the permission of your healthcare provider.

6. Liver Diseases

Patients with liver disease should take Entamizole DS with caution. The liver does the metabolism and excretion of drugs in the body. However, in cases where the liver is not working efficiently due to failure or disease, the drugs get accumulated in the body. That jeopardizes the health of the person.

7. Mental Disorders

If you have any mental disorder like depression and anxiety, you must take Entamizole DS with caution as it can worsen the preexisting condition. Always tell your healthcare provider about the health conditions you have.

8. Alcohol Intake

You must avoid alcohol intake with Entamizole DS as it may cause severe adverse effects.

9. Peripheral Neuropathy

Entamizole DS can exacerbate peripheral neuropathy. Therefore, avoid its use if you already have the same condition.

10. Anticoagulants or Bleeding Disorders

If you are taking anticoagulants for thinning of your blood, or you have any bleeding disorder, take Entamizole DS with caution on the advice of a healthcare provider.

How to use Entamizole DS Tablet 500mg/400mg?

  • Entamizole DS tablets should be consumed whole with a glass of water.
  • It can be taken on an empty stomach or after eating food.
  • Do not crush or chew the medicine.
  • Do not use the drug after the mentioned expiry date.

Entamizole Side Effects

Entamizole is a generally safe drug. However, sometimes it can cause side effects, such as:

  • Abdominal pain
  • Vomit-containing coffee grounds
  • Blood in stool
  • Constipation
  • Black stools
  • Acid reflux
  • Anemia
  • Elevation of liver enzymes
  • Diarrhea
  • Serum sickness
  • Risk of infections
  • Crystalluria
  • Eye discomfort
  • Gastric discomfort
  • Lethargy and body pain
  • Headache
  • Hearing impairment
  • Nausea
  • Pancreatitis
  • Sleep disorders
  • Vision disorders
  • Altered taste

Drug Interactions

Entamizole DS can interact with certain drugs. However, a drug interaction does not mean that the patient stops taking the medication on their own. Instead, the correct protocol is to report to their healthcare provider, who will take the required necessary steps. They might change the drug or their timings to prevent drug interaction.

Medications with which Entamizole DS can interact are:

  • Probenecid
  • Blood thinners like warfarin
  • Allopurinol
  • Oral birth control pills containing estrogen and progesterone
  • Other antibiotics like chloramphenicol, tetracyclines, sulfonamides, and macrolides
  • Cholesterol-lowering drugs like atorvastatin, rosuvastatin, and other statins
  • Ergot alkaloids
  • Colchicine
  • Oral hypoglycemic agents like repaglinide, rosiglitazone, nateglinide, and pioglitazone
  • Quetiapine
  • Antiarrhythmic drugs like amiodarone and procainamide
  • Benzodiazepine like diazepam, midazolam and triazolam
  • Disulfiram
  • Alcohol

To prevent drug interactions, you should give a detailed history to your healthcare provider. Include your current medical conditions about your physical and mental health alongside previous experience with any health complications. Similarly, also enlist your risk factors. It will give the doctor a holistic view of your health, and they can accordingly adjust the dosage, frequency, or type of the medicine to prevent drug interactions.

Storage Conditions

  • Keep the medicine out of sight and reach of children.
  • Store at room temperature.


Frequently Asked Questions

What is the price of Entamizole DS Tablet 500mg/400mg in Pakistan?

The Entamizole DS Tablet 500mg/400mg price in Pakistan is Rs. 113.67

What is Entamizole DS Tablet 500mg/400mg used for?

Entamizole DS Tablet 500mg/400mg is used in the following conditions:
  • Anaerobic infection/clostridium difficile infection
  • Pylori eradication
  • Fistulating Crohn's disease
  • Pelvic inflammatory disease
  • Surgical prophylaxis
  • Invasive intestinal amoebiasis
  • Extra-intestinal amoebiasis
  • Liver abscess
  • Urogenital trichomoniasis
  • Giardiasis
  • Intestinal amebiasis

What is Entamizole DS Tablet 500mg/400mg composed of?

Entamizole DS Tablet 500mg/400mg is composed of:
  • Diloxanide Furoate
  • Metronidazole

Do you need a prescription to buy Entamizole DS Tablet 500mg/400mg?

To buy Entamizole DS Tablet 500mg/400mg you must have a prescription signed by your doctor.


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