Excedrin-Xtra tablet 35mg / 450mg

About Excedrin-Xtra tablet 35mg / 450mg

Excedrin-Xtra Tablet Uses

• Relieves painful muscle spasm
• Used for backache and neck pain from muscle strain
• Helps in sprains, sports injuries and stiff muscles
• Reduces pain and fever linked with musculoskeletal conditions

Excedrin-Xtra Tablet Benefits

• Two medicines in one tablet for spasm and pain
• Eases stiffness so movement becomes easier
• Short courses usually give quick relief

What Experts Say

Excedrin-Xtra combines orphenadrine with paracetamol. Orphenadrine relaxes tight skeletal muscles and also has mild anticholinergic and pain-modifying effects. It is a prescription tablet and is usually meant for short courses of a few days, not long term use.

Paracetamol adds pain and fever relief by acting in the brain, without the stomach irritation seen with many anti-inflammatory tablets. Together they treat both the cramp and the pain it causes. Rest, gentle stretching and heat packs often speed recovery alongside the tablet.

The tablet can cause drowsiness, dry mouth and blurred vision. Total paracetamol from all products must stay within safe daily limits to protect the liver. Do not use it for chronic pain without a doctor's plan, because side effects build with longer use. Older adults are more sensitive to dizziness and confusion, so they need extra care with this combination and a lower starting dose.

Drug Class

• Skeletal muscle relaxant (orphenadrine)
• Analgesic and antipyretic (paracetamol)

Excedrin-Xtra tablet 35mg / 450mg formula

• Orphenadrine
• Paracetamol

Available forms

• Tablet

How to use Excedrin-Xtra tablet 35mg / 450mg?

• Take Excedrin-Xtra exactly as prescribed, usually with water after food.
• Do not take any other paracetamol containing product at the same time.
• Do not exceed the daily dose your doctor has advised.
• Use for a short course and see the doctor if pain continues.

Drug Interactions

• Other paracetamol products: Taking more than one raises the risk of liver damage from overdose.
• Alcohol and sedatives: They add to drowsiness and, with paracetamol, can stress the liver.
• Anticholinergic drugs: Antihistamines and some antidepressants can add to dry mouth, constipation and blurred vision.
• Warfarin: Regular paracetamol use can increase the blood thinning effect.

Risks and warnings

• Liver safety: Too much paracetamol can seriously damage the liver. Avoid alcohol and other paracetamol products.
• Drowsiness: It can cause dizziness and blurred vision, so avoid driving until you know how it affects you.
• Glaucoma, prostate and bladder: Orphenadrine can worsen angle-closure glaucoma, prostate enlargement and difficulty passing urine.
• Myasthenia gravis and stomach blockage: It should not be used in these conditions.

Excedrin-Xtra Tablet Side Effects

• Drowsiness
• Dry mouth
• Blurred vision
• Dizziness
• Constipation
• Difficulty passing urine
• Fast heartbeat
• Nausea

Storage Conditions

• Store below 30°C in a cool, dry place.
• Protect from moisture and light.
• Keep out of reach of children.