Glandin E-2 Vaginal Tablet 3mg

About Glandin E-2 Vaginal Tablet 3mg

Glandin E-2 Uses

• Cervical ripening before labor induction
• Induction of labor in women at or near full term
• Management of missed miscarriage
• Termination of pregnancy for medical reasons, under specialist care

Glandin E-2 Benefits

• Softens and opens the cervix to prepare it for delivery
• Reduces the need for surgical intervention in some labor inductions
• Works directly at the site of action with a targeted local effect

What Experts Say

Dinoprostone is a synthetic form of prostaglandin E2, a natural hormone-like substance the body produces to prepare for childbirth. It softens the collagen fibers in the cervix and increases water content in the tissue, making the cervix thinner and more able to dilate. It also stimulates the uterine muscle to contract.

Obstetricians use dinoprostone tablets specifically when the cervix is not yet ready for labor, a state doctors call an unfavorable cervix. It is placed in the upper vagina under close monitoring, since it can trigger contractions within a few hours. Continuous fetal heart rate monitoring is standard practice after insertion because contractions can sometimes become too frequent or strong.

Labor induction is becoming more common as more pregnancies are monitored closely for complications like high blood pressure or prolonged pregnancy beyond the due date. Because this medicine directly affects uterine activity, it is only ever given inside a hospital setting with a doctor and midwife present, never for home or unsupervised use.

Drug Class

• Prostaglandin E2 analogue

Glandin E-2 Vaginal Tablet 3mg formula

• Dinoprostone

Available forms

• Vaginal Tablet

How to use Glandin E-2 Vaginal Tablet 3mg?

• Allow the healthcare provider to insert the tablet high into the vagina.
• Remain lying down for the time period advised by your doctor after insertion.
• Report any strong or continuous contractions immediately to hospital staff.
• Follow all monitoring appointments as scheduled by your obstetrician.

Drug Interactions

• Oxytocin: Giving oxytocin too soon after dinoprostone can cause dangerously strong uterine contractions and must be spaced out under medical supervision.
• Other prostaglandins: Combining with other prostaglandin-based medicines is avoided due to additive uterine effects.

Risks and warnings

• Uterine hyperstimulation: The tablet can cause excessively strong or frequent contractions that may reduce oxygen supply to the baby.
• Prior cesarean section: Use is generally avoided in women with a previous C-section scar due to the risk of uterine rupture.
• Fetal distress: Continuous monitoring is required because contractions can sometimes cause changes in the baby's heart rate.
• Hospital use only: This medicine must never be self-administered and requires close medical supervision at all times.

Glandin E-2 Side Effects

• Uterine contractions that are stronger than expected
• Nausea
• Vomiting
• Diarrhea
• Mild fever
• Headache
• Vaginal warmth or irritation at the insertion site

Storage Conditions

• Store Glandin E-2 tablets in a refrigerator between 2°C and 8°C.
• Keep the tablet in its original foil until the moment of use.
• Protect from light and avoid freezing.
• Keep out of reach of children.