Januvia tablet 100mg

About Januvia tablet 100mg

Januvia Uses

• Control of blood sugar in adults with type 2 diabetes.
• Use alone when metformin is not suitable.
• Add on treatment with metformin, a sulfonylurea or insulin, as prescribed.
• Use together with diet and regular exercise.

Januvia Benefits

• Lowers blood sugar after meals and on fasting.
• Low risk of hypoglycemia when used alone.
• Once daily dosing is simple to follow.
• Does not usually cause weight gain.

What Experts Say

Sitagliptin blocks the DPP-4 enzyme, which normally breaks down natural gut hormones called incretins. Higher incretin levels help the pancreas release insulin when blood sugar is high and reduce extra sugar release from the liver. This glucose dependent action is why low sugar episodes are uncommon.

The 100 mg dose is the usual adult dose and can be taken with or without food. It is often chosen when weight gain or hypoglycemia is a concern. Regular blood sugar and HbA1c checks help doctors judge how well it is working, and diet and exercise remain essential. Many people in Pakistan use it alongside metformin when sugar stays high.

The dose is lowered in people with reduced kidney function, so kidney tests are important. Severe stomach pain that does not go away may signal pancreatitis, and the medicine should be stopped and a doctor contacted at once. It is not for type 1 diabetes or diabetic ketoacidosis. Never stop or change the dose without the doctor's advice.

Drug Class

• DPP-4 inhibitor (gliptin)

Januvia tablet 100mg formula

• Sitagliptin

Available forms

• Tablet

How to use Januvia tablet 100mg?

• Adults: one Januvia 100 mg tablet once daily, as prescribed.
• Swallow with water, with or without food.
• Dose is reduced in moderate to severe kidney impairment, as advised by the doctor.
• Not recommended for children, and not for type 1 diabetes.
• Continue diet, exercise and regular blood sugar checks.

Drug Interactions

• Insulin and sulfonylureas: Combined use may cause low blood sugar, so their doses may need lowering.
• Digoxin: Sitagliptin may slightly raise digoxin levels, so monitoring is advised.
• Metformin: Often combined safely, as directed by the doctor.
• ACE inhibitors: They may slightly increase the chance of swelling of the face or lips.

Risks and warnings

• Pancreatitis: Severe, lasting stomach pain needs urgent medical review and stopping the medicine.
• Kidney impairment: Dose adjustment is needed, so kidney tests should be done regularly.
• Low blood sugar: Risk rises when combined with insulin or sulfonylureas.
• Allergic reactions: Swelling of the face or throat, or severe rash, needs emergency care.
• Joint pain: Severe joint pain has been reported and should be reported to the doctor.

Januvia Tablet 100mg Side Effects

• Headache
• Stuffy or runny nose
• Sore throat
• Upper respiratory infection
• Stomach upset
• Diarrhea
• Joint pain
• Low blood sugar with other diabetes medicines

Storage Conditions

• Store below 30 C in a dry place, away from heat and humidity.
• Keep tablets in the original blister until use.
• Do not use after the expiry date on the pack.
• Keep out of reach of children.