Lodopin-V Tablet 10 mg / 160 mg

About Lodopin-V Tablet 10 mg / 160 mg

Lodopin-V Tablet 10 mg / 160 mg Uses

• Treatment of high blood pressure (hypertension)
• Blood pressure control when a single antihypertensive drug is not enough
• Long-term management of hypertension to lower stroke and heart attack risk
• Combination therapy for patients already stable on separate amlodipine and valsartan doses

Lodopin-V Tablet 10 mg / 160 mg Benefits

• Combines two blood pressure lowering actions in one tablet
• Improves adherence by reducing the number of daily pills
• Provides steadier round-the-clock blood pressure control
• Reduces reflex fluid retention sometimes seen with amlodipine alone
• Supports long-term protection of the heart, kidneys and blood vessels

What Experts Say

Amlodipine is a calcium channel blocker that relaxes blood vessel walls by limiting calcium entry into smooth muscle cells. Valsartan is an angiotensin receptor blocker that stops angiotensin II from tightening blood vessels and raising fluid retention.

Combining the two drugs targets blood pressure through separate pathways, so the effect is often stronger than either drug alone at a similar dose. Valsartan also blunts the ankle swelling that amlodipine can cause, since it relaxes veins as well as arteries and improves fluid balance.

Doctors prescribe the 10 mg amlodipine and 160 mg valsartan strength for patients whose blood pressure stays high on lower combination doses or on amlodipine monotherapy. Kidney function and potassium levels are usually checked before starting this higher-strength combination, since valsartan reduces aldosterone-driven sodium and water retention.

Drug Class

• Calcium Channel Blocker + Angiotensin Receptor Blocker (ARB) Combination

Lodopin-V Tablet 10 mg / 160 mg formula

• Amlodipine Besylate + Valsartan

Available forms

• Tablet

How to use Lodopin-V Tablet 10 mg / 160 mg?

• Take one tablet once daily, with or without food.
• Swallow the tablet whole with a glass of water.
• Take it at the same time every day for consistent blood pressure control.
• Do not stop the tablet suddenly without consulting a doctor.
• Continue regular blood pressure checks while on this combination.

Drug Interactions

• Potassium-Sparing Diuretics: Combining these with valsartan can raise blood potassium to unsafe levels.
• Lithium: Valsartan can raise lithium levels in the blood, increasing the risk of lithium toxicity.
• NSAIDs: Regular use of painkillers like ibuprofen or diclofenac can reduce the blood pressure lowering effect and stress the kidneys.
• Other Blood Pressure Medicines: Combining with other antihypertensives can cause an excessive drop in blood pressure.
• Strong CYP3A4 Inhibitors: Drugs like ketoconazole or ritonavir can raise amlodipine blood levels and increase side effects.
• Simvastatin: High-dose simvastatin combined with amlodipine raises the risk of muscle-related side effects.

Risks and warnings

• Pregnancy: Avoid this tablet during pregnancy, since the valsartan component can cause fetal kidney injury and even death when used in the second and third trimester.
• Low Blood Pressure: Use with caution in patients prone to low blood pressure, since the combined effect of both drugs can cause dizziness or fainting, especially after the first dose.
• Fluid Retention And Swelling: Report new ankle or leg swelling to a doctor, since amlodipine can still cause mild edema despite the valsartan component.
• Kidney Function: Patients with kidney artery narrowing or reduced kidney function need monitoring, since valsartan can further lower kidney blood flow.
• Liver Impairment: Use cautiously in significant liver disease, since both drug components are processed by the liver.
• High Potassium Levels: Avoid potassium supplements or salt substitutes without medical advice, since valsartan can raise blood potassium.

Lodopin-V Tablet 10 mg / 160 mg Side Effects

• Dizziness
• Headache
• Fatigue
• Swelling of the ankles or feet
• Low blood pressure
• Nasal congestion or upper respiratory symptoms
• Flushing
• Palpitations
• Nausea
• Back pain

Storage Conditions

• Store below 30°C in a cool, dry place away from direct sunlight.
• Keep the tablets in their original blister pack until use.
• Protect from moisture and excess humidity.
• Keep out of reach of children.
• Discard any unused tablets after the printed expiry date.