Mefac Forte Tablet 500mg

About Mefac Forte Tablet 500mg

Mefac Forte Tablet 500mg Uses

• Relieves menstrual cramps and period pain
• Eases headaches and migraine related pain
• Reduces mild to moderate pain from rheumatoid arthritis
• Helps control fever and general body aches
• Used for pain after minor dental or surgical procedures

Mefac Forte Tablet 500mg Benefits

• Fast acting relief for short term pain episodes
• Widely used and affordable option for menstrual pain in Pakistan
• Combines pain relief with anti-inflammatory action
• Available in a convenient tablet form for adults

What Experts Say

Mefenamic acid belongs to the fenamate group of nonsteroidal anti-inflammatory drugs used widely for short term pain relief across Pakistan, particularly for menstrual and musculoskeletal pain. It blocks cyclooxygenase enzymes, reducing the prostaglandins responsible for pain, cramping, swelling and fever.

Clinical references describe mefenamic acid as particularly effective for menstrual pain because it reduces uterine prostaglandin levels, which are often elevated during painful periods and contribute to cramping. It is generally used for short courses rather than continuous long term therapy.

Medical guidance limits mefenamic acid use to a maximum of about seven days at a time, since prolonged use raises the risk of stomach irritation, kidney strain and rare blood disorders that require close monitoring. Patients with existing stomach, kidney or liver disease need medical advice before use.

Drug Class

• Nonsteroidal Anti-Inflammatory Drug (NSAID)
• Fenamate Derivative

Mefac Forte Tablet 500mg formula

• Mefenamic Acid

Available forms

• Tablet

How to use Mefac Forte Tablet 500mg?

• Take with food or a glass of milk to reduce stomach upset
• Swallow the tablet whole with water
• Do not use for more than seven days without medical advice
• Use the lowest effective dose needed to control symptoms

Drug Interactions

• Aspirin and Other NSAIDs: Combined use raises the risk of stomach bleeding.
• Blood Thinners (Warfarin): Mefenamic acid can increase bleeding risk with anticoagulants.
• Diuretics and ACE Inhibitors: Mefenamic acid may reduce their effectiveness and stress the kidneys.
• Lithium: Mefenamic acid can raise lithium levels, increasing toxicity risk.

Risks and warnings

• Gastrointestinal Risk: May cause stomach ulcers or bleeding, especially with use beyond seven days.
• Kidney Function: Avoid in patients with significant kidney disease or dehydration.
• Blood Disorders: Rare cases of reduced blood cell counts have been reported with prolonged use.
• Pregnancy: Avoid in the third trimester due to risks to the unborn baby.
• Diarrhea: Discontinue if severe diarrhea develops during treatment.

Mefac Forte Tablet 500mg Side Effects

• Stomach upset or indigestion
• Diarrhea
• Headache or drowsiness
• Skin rash
• Heartburn
• Stomach ulcers or gastrointestinal bleeding with prolonged use
• Reduced kidney function with long term or high dose use
• Rare blood disorders such as low platelet or white cell counts
• Severe allergic reaction with swelling of the face or throat

Storage Conditions

• Store below 30°C in a dry place
• Protect from direct sunlight
• Keep out of reach of children
• Do not use after the expiry date on the pack