Ofylin Tablet 40mg

About Ofylin Tablet 40mg

Ofylin Tablet Uses

• Manage bronchial asthma
• Control chronic obstructive pulmonary disease (COPD)
• Relieve wheezing and breathlessness
• Ease chronic bronchitis symptoms
• Reduce chest tightness caused by airway narrowing

Ofylin Tablet Benefits

• Opens narrowed airways for easier breathing
• Carries a lower risk of stomach and heart side effects compared to older bronchodilators
• Suitable for long term asthma and COPD control
• Works well alongside inhalers for combined therapy
• Improves lung function with regular use

What Experts Say

Doxofylline belongs to the methylxanthine class of bronchodilators. It works by inhibiting the phosphodiesterase enzyme, particularly PDE4, which relaxes the smooth muscles lining the airways. This action widens the bronchial passages and makes breathing easier for people with asthma or COPD.

Pulmonologists often prefer doxofylline over older xanthine drugs because it has a lower affinity for adenosine receptors. This receptor profile is linked to fewer cardiac and central nervous system side effects than theophylline while still providing effective bronchodilation for long term respiratory control.

Clinicians recommend caution in elderly patients and those with liver, kidney or heart conditions since drug clearance can be reduced. Doctors typically review other medications being taken, since certain antibiotics and enzyme inhibitors can raise doxofylline levels in the blood and increase the chance of side effects.

Drug Class

• Methylxanthine derivative
• Bronchodilator
• Phosphodiesterase (PDE4) inhibitor
• Respiratory system agent

Ofylin Tablet 40mg formula

• Doxofylline

Available forms

• Tablet

How to use Ofylin Tablet 40mg?

• Take Ofylin Tablet 40mg exactly as prescribed by your doctor, usually two to three times a day.
• Swallow the tablet whole with a glass of water.
• Take it after meals to reduce stomach upset.
• Do not crush or chew the tablet unless your doctor advises otherwise.
• Take doses at evenly spaced times to maintain steady levels in the blood.
• Do not stop the medicine suddenly without consulting your doctor.

Drug Interactions

• Erythromycin And Other Macrolides: These antibiotics can raise doxofylline blood levels and increase the risk of side effects.
• Cimetidine: This acid reducing drug can slow doxofylline clearance and raise its concentration in the body.
• Phenytoin: This seizure medicine can lower doxofylline effectiveness by speeding up its breakdown.
• Ciprofloxacin And Other Fluoroquinolones: These antibiotics can interfere with xanthine metabolism and raise toxicity risk.
• Propranolol And Other Beta Blockers: These can reduce the bronchodilating effect of doxofylline while also raising interaction risk.
• Ephedrine: Combined use may increase the chance of nervousness, rapid heartbeat and insomnia.

Risks and warnings

• Cardiac Conditions: Use with caution in patients with arrhythmia, heart failure or a recent heart attack since doxofylline can raise heart rate.
• Peptic Ulcer History: Doxofylline may worsen stomach acidity and should be used carefully in patients with a history of ulcers.
• Pregnancy And Breastfeeding: Avoid use during pregnancy unless clearly needed and do not use while breastfeeding.
• Elderly Patients: Doctors monitor patients over 60 years closely since drug clearance slows with age.
• Smokers: Smoking can change how quickly the body clears doxofylline, so a dose adjustment may be needed.

Ofylin Tablet Side Effects

• Headache
• Nausea and vomiting
• Stomach pain or discomfort
• Difficulty sleeping (insomnia)
• Irritability or restlessness
• Increased heart rate
• Irregular heartbeat (palpitations)
• Faster breathing rate
• Heartburn or acid reflux

Storage Conditions

• Store at room temperature below 30°C in a dry place.
• Keep the strip away from direct sunlight and moisture.
• Keep the tablets in their original blister pack until use.
• Keep out of reach of children.
• Discard expired tablets safely through a pharmacy take back program.