Puroxan Tablet 400mg

About Puroxan Tablet 400mg

Puroxan Tablet 400mg Uses

• Bronchial asthma
• Chronic obstructive pulmonary disease (COPD)
• Chronic bronchitis with bronchospasm
• Wheezing and breathlessness associated with airway obstruction

Puroxan Tablet 400mg Benefits

• Relaxes tightened airway muscles for easier breathing
• Reduces frequency of wheezing episodes
• Carries a lower risk of stomach and heart side effects than older theophylline drugs
• Works well alongside inhaled bronchodilators

What Experts Say

Pulmonologists in Pakistan often add doxofylline to an inhaler based regimen when asthma or COPD symptoms are not fully controlled, since it works through a different pathway than beta agonists and steroids.

Doxofylline is generally preferred over older theophylline because it has a wider safety margin, with a lower tendency to cause palpitations, tremors, or stomach irritation at standard doses. Routine blood level monitoring, needed with theophylline, is usually not required with doxofylline.

Pakistan has a high prevalence of chronic respiratory disease linked to smoking, indoor smoke exposure, and air pollution, so physicians recommend combining bronchodilator tablets with inhaler therapy, smoking cessation, and regular follow up for lasting symptom control. Long term treatment plans increasingly favor doxofylline over older xanthine drugs, since fewer clinic visits for blood level checks make it more practical in busy outpatient settings.

Drug Class

• Xanthine derivative (bronchodilator)

Puroxan Tablet 400mg formula

• Doxofylline

Available forms

• Tablet

How to use Puroxan Tablet 400mg?

• The usual dose is one tablet by mouth twice daily, or as directed by a doctor.
• A full glass of water helps with swallowing the tablet.
• Taking the tablet after meals can reduce stomach upset.
• The tablet should not be crushed or chewed.
• The full course is recommended even if breathing feels better.

Drug Interactions

• Theophylline and other xanthines: Combined use raises the risk of toxicity such as palpitations and seizures.
• Fluoroquinolone antibiotics: Drugs such as ciprofloxacin can raise doxofylline blood levels.
• Cimetidine: This acid reducer can slow doxofylline clearance and increase side effects.
• Beta blockers: These can reduce the bronchodilator effect of doxofylline.

Risks and warnings

• Cardiac conditions: Caution is needed in patients with irregular heartbeat or heart disease, since xanthine derivatives can affect heart rhythm.
• Seizure disorder: This tablet is best avoided in people with a history of seizures, since doxofylline can lower the seizure threshold.
• Peptic ulcer: Caution is advised in active peptic ulcer disease, since it may worsen gastric irritation.
• Liver or kidney disease: A dose adjustment may be needed since impaired organ function can raise drug levels.
• Pregnancy: This tablet should only be used when clearly needed and under medical supervision, since safety data in pregnancy is limited.

Puroxan Tablet 400mg Side Effects

• Nausea or stomach discomfort
• Headache
• Palpitations
• Insomnia or restlessness
• Dizziness
• Heartburn
• Rare allergic skin reactions

Storage Conditions

• Store below 30 degrees Celsius in a dry place.
• Keep the blister strip sealed until use.
• Protect from direct light and moisture.
• Keep out of reach of children.