About Preston Tablet 250mg
Preston Tablet 250mg contains Mefenamic Acid, an NSAID used for pain and menstrual cramps relief.
Preston Tablet Uses
- Menstrual pain (dysmenorrhea)
- Mild to moderate pain relief
- Fever reduction
- Headache and migraine relief
- Dental pain after extraction
- Postoperative pain
- Joint and muscle pain
- Osteoarthritis and rheumatoid arthritis pain
Preston Tablet Benefits
- Fast pain relief within about an hour
- Reduces heavy menstrual blood flow along with cramping
- Dual action against both pain and inflammation
- Effective for short term fever control
- Affordable generic option compared to branded fenamates
What Experts Say
Mefenamic acid belongs to the fenamate class of nonsteroidal anti-inflammatory drugs. It works by blocking the cyclooxygenase enzymes that produce prostaglandins, the chemical messengers responsible for pain, swelling and fever. This dual action against pain and inflammation makes it a common choice for conditions where inflammation is the main driver of discomfort.
Clinical studies support its use in dysmenorrhea because it lowers prostaglandin levels in the uterine lining, which eases cramping and can reduce heavy menstrual blood flow. The onset of relief is usually within 30 to 60 minutes of an oral dose, and the effect typically lasts around six hours, which is why dosing every six hours is standard practice.
Like other NSAIDs, mefenamic acid carries a risk of gastrointestinal irritation with prolonged use, so short courses at the lowest effective dose are generally recommended. Patients with kidney disease, heart conditions or a history of stomach ulcers need closer monitoring before starting therapy, and elderly patients are usually advised to use it for the shortest duration possible.
Drug Class
- Nonsteroidal Anti-Inflammatory Drug (NSAID)
- Fenamate Derivative
- Analgesic and Antipyretic Agent
Preston Tablet 250mg Uses in Urdu
- ماہواری کے درد میں آرام کے لیے
- ہلکے سے درمیانے درجے کے درد میں
- بخار کم کرنے کے لیے
- سر درد اور دانت کے درد میں
- جوڑوں اور پٹھوں کے درد میں
- آپریشن کے بعد ہونے والے درد میں
Preston Tablet 250mg formula
How to use Preston Tablet 250mg?
- Initial dose of 500mg (two tablets), then 250mg every 6 hours as needed for pain.
- With food or milk to reduce stomach upset.
- Whole tablet with a full glass of water, not crushed or chewed.
- No more than 7 days of continuous use without medical advice.
- At the first sign of menstrual pain for best results.
Drug Interactions
- Aspirin and Other NSAIDs: Combined use raises the risk of stomach bleeding and ulcers.
- Warfarin and Blood Thinners: Mefenamic acid can increase bleeding risk when taken together.
- ACE Inhibitors and ARBs: Blood pressure lowering effect may be reduced, with added strain on the kidneys.
- Diuretics: Effectiveness may drop and kidney function may be affected.
- Lithium: Blood lithium levels can rise to unsafe levels.
- Methotrexate: Risk of methotrexate toxicity increases when combined with this medicine.
Risks and warnings
- Gastrointestinal Risk: Long term use can cause stomach ulcers or bleeding, especially in older adults.
- Cardiovascular Risk: NSAIDs may increase the risk of heart attack or stroke with prolonged use.
- Kidney Function: Reduced kidney function can occur with extended use or in patients with existing kidney disease.
- Pregnancy Caution: Third trimester use is not recommended due to risk of premature closure of a fetal blood vessel.
- Peptic Ulcer History: Active stomach ulcers or a history of recurrent ulcers make this medicine unsuitable.
- Asthma Sensitivity: Patients with aspirin sensitive asthma need caution due to possible bronchospasm.
Preston Tablet 250mg Side Effects
- Stomach pain or indigestion
- Heartburn
- Nausea and diarrhea
- Dizziness or drowsiness
- Headache
- Fluid retention and mild swelling
- Skin rash or itching
- Ringing in the ears
- Gastrointestinal bleeding or black stools (serious, seek immediate care)
- Signs of kidney problems such as reduced urination (serious)
- Severe allergic reaction with facial swelling or difficulty breathing (serious)
Storage Conditions
- Store below 30°C in a cool, dry place.
- Keep the strip in its original packaging away from direct sunlight.
- Keep out of reach of children.
- Avoid storing in the bathroom or near moisture.
- Discard unused tablets after the expiry date printed on the pack.
