Vastarel MR Tablet 35mg

About Vastarel MR Tablet 35mg

Vastarel MR Tablet Uses

• Add on treatment for chronic stable angina not controlled by first line heart medicines
• Reducing frequency of chest pain episodes in coronary artery disease
• Supporting heart muscle energy use during reduced blood flow
• Used alongside beta blockers, nitrates or calcium channel blockers as directed

Vastarel MR Tablet Benefits

• Improves exercise tolerance in people with stable angina
• Modified release formula allows twice daily dosing
• Does not lower blood pressure or heart rate, unlike other anti anginal medicines
• Can be added to existing heart medicines without major dose adjustment in most adults

Drug Class

• Metabolic anti anginal agent
• Fatty acid oxidation inhibitor
• Used as adjunct therapy, not a first line angina medicine

What Experts Say

Trimetazidine works differently from most angina medicines because it does not widen blood vessels or slow the heart rate. Instead it shifts how heart cells produce energy, favoring glucose over fatty acids, which needs less oxygen for the same output during periods of restricted blood flow.

Because of this mechanism, cardiologists usually add it on top of a beta blocker, calcium channel blocker or nitrate rather than using it alone, especially when chest pain continues despite standard treatment. This add on role is why current guidelines position it as second line therapy.

Monitoring matters because trimetazidine can worsen or unmask movement disorders in some patients, so doctors review symptoms like tremor or stiffness during follow up. Kidney function also guides dosing, since reduced clearance in kidney disease raises drug levels in the body.

Vastarel MR Tablet 35mg formula

• Trimetazidine Dihydrochloride 35mg

Available forms

• Tablet

How to use Vastarel MR Tablet 35mg?

• Take one tablet twice daily with morning and evening meals
• Swallow the tablet whole, do not crush or split the modified release tablet
• Take at consistent times each day for steady blood levels
• Continue other prescribed heart medicines unless a doctor advises a change
• Do not stop suddenly without consulting a doctor

Drug Interactions

• Metoclopramide and other dopamine blocking medicines: Combined use raises the risk of movement related side effects
• Levodopa or other Parkinson's medicines: May reduce their effectiveness so combined use needs monitoring
• Sedating medicines: May add to dizziness or drowsiness when combined
• Other anti anginal medicines: Generally safe to combine but should be guided by a cardiologist

Risks and warnings

• Parkinson's disease or movement disorders: Avoid use since symptoms may worsen
• Severe kidney impairment: Not recommended when creatinine clearance is below thirty
• Pregnancy and breastfeeding: Avoid unless specifically advised by a doctor
• Elderly patients: Use with caution and monitor for tremor or unsteady movement
• Driving or operating machinery: Use caution if dizziness or drowsiness occurs

Vastarel MR Tablet 35mg Side Effects

• Dizziness or lightheadedness
• Headache
• Nausea or stomach discomfort
• General weakness or fatigue
• Palpitations or irregular heartbeat sensation
• Swelling of the ankles or feet
• Tremor, stiffness or unsteady movement in rare cases

Storage Conditions

• Store below thirty degrees Celsius in a dry place
• Keep tablets in the original blister pack until use
• Protect from direct sunlight and moisture
• Keep out of reach of children
• Discard tablets after the expiry date printed on the pack