Vermox Tablet 100mg

About Vermox Tablet 100mg

Vermox Tablet Uses

• Treatment of roundworm (Ascaris lumbricoides) infection
• Treatment of whipworm (Trichuris trichiura) infection
• Treatment of hookworm (Ancylostoma duodenale and Necator americanus) infection
• Treatment of pinworm (Enterobius vermicularis) infection
• Treatment of mixed intestinal worm infections

Vermox Tablet Benefits

• Clears multiple worm species with one treatment course
• Works locally in the gut with minimal absorption into the bloodstream
• Simple twice daily dosing schedule for a short 3 day course
• Helps restore normal nutrient absorption disrupted by parasites
• Suitable for most adults and children above 2 years under medical guidance

What Experts Say

Mebendazole works by binding to the beta tubulin protein inside worm cells. This blocks the parasite's ability to absorb glucose, which is its main energy source. Without glucose uptake, the worm becomes immobilized and eventually dies within the intestine over several days.

The 100mg strength is designed for a twice daily, three day course for most roundworm, whipworm and hookworm infections, since sustained drug exposure improves cure rates for these species. Pinworm infection responds to a single 100mg dose because the parasite's lifecycle in the lower bowel needs a shorter contact period.

Mebendazole has poor systemic absorption, so it acts mainly within the gut lumen rather than the whole body, which keeps its side effect profile relatively mild for most patients. Clinical evidence supports repeating the course after two to three weeks if eggs or symptoms persist, since reinfection from contaminated hands or food is common.

Drug Class

• Anthelmintic
• Benzimidazole Derivative

Vermox Tablet 100mg formula

• Mebendazole 100mg

Available forms

• Tablet

How to use Vermox Tablet 100mg?

• Take one 100mg tablet in the morning and one in the evening for 3 consecutive days for roundworm, whipworm and hookworm infections
• Take a single 100mg tablet as one dose for pinworm infection, with a repeat dose after 2 weeks if advised
• Swallow the tablet whole or chew it thoroughly with a small amount of water
• Take with or without food, though a fatty meal may improve absorption
• Treat all household members together to prevent reinfection from pinworm
• Wash hands, bedding and undergarments regularly during treatment to lower reinfection risk

Drug Interactions

• Carbamazepine: May reduce mebendazole blood levels and lower its effectiveness
• Phenytoin: May decrease mebendazole plasma concentration through enzyme induction
• Cimetidine: May increase mebendazole blood levels and raise the chance of side effects
• Metronidazole: Combined use has been linked with rare cases of severe skin reactions
• Ritonavir: May significantly lower mebendazole plasma levels through metabolic interaction

Risks and warnings

• Pregnancy: Avoid use during the first trimester unless clearly necessary and advised by a doctor
• Liver Disease: Use with caution in patients with existing liver impairment
• Young Children: Not generally recommended under 2 years of age due to limited safety data
• Crohn Disease: Rare cases of reduced drug absorption reported in inflammatory bowel conditions
• Repeated Courses: Prolonged or repeated high dose use may need liver function monitoring

Vermox Tablet Side Effects

• Abdominal pain or cramping
• Diarrhea
• Nausea
• Flatulence
• Headache
• Dizziness
• Skin rash or itching
• Elevated liver enzymes on rare testing
• Severe allergic reaction with swelling or breathing difficulty
• Unusual bruising or bleeding in rare cases

Storage Conditions

• Store below 30°C in a cool, dry place
• Keep the tablet strip in its original packaging away from light
• Keep out of reach of children
• Avoid storing in the bathroom or near direct moisture
• Discard any unused tablets after the expiry date printed on the pack