Zolt Suspension 250mg / 200mg

About Zolt Suspension 250mg / 200mg

Zolt Suspension 250mg / 200mg Uses

• Treatment of intestinal amoebiasis caused by Entamoeba histolytica
• Treatment of giardiasis and other intestinal protozoal infections
• Management of amoebic liver abscess alongside other therapy
• Clearing the intestinal cyst stage of amoebic infection after acute treatment

Zolt Suspension 250mg / 200mg Benefits

• Combines two antiparasitic agents for wider coverage in one dose
• Clears both active infection and the cyst carrier stage
• Liquid form suits children and adults who cannot swallow tablets
• Short treatment course compared to some other antiparasitic regimens

What Experts Say

Metronidazole works by damaging the DNA of anaerobic parasites and bacteria once it is activated inside their cells, which stops them from multiplying and eventually kills them. Diloxanide furoate acts mainly in the intestinal lumen, where it is converted to diloxanide and kills the cyst forming stage of the amoeba.

Using both drugs together allows the combination to treat active tissue infection and the intestinal cyst stage at the same time, which lowers the chance of the infection coming back after treatment stops. This dual action is one reason combination antiamoebic suspensions are commonly prescribed in Pakistan for children and adults with confirmed amoebiasis.

Doctors usually base the dose on body weight for children and use a fixed adult dose for older patients, given for a set number of days rather than as a single dose. Alcohol should be avoided during treatment and for at least a day after the last dose, since metronidazole can cause a strong reaction when combined with alcohol.

Drug Class

• Antiamoebic and antiprotozoal combination
• Nitroimidazole plus amide derivative

Zolt Suspension 250mg / 200mg formula

• Diloxanide Furoate + Metronidazole

Available forms

• Suspension

How to use Zolt Suspension 250mg / 200mg?

• Shake the bottle well before each dose
• Measure the dose with the measuring cup or spoon provided, not a kitchen spoon
• Take Zolt Suspension after meals to reduce stomach upset
• Complete the full course even if symptoms improve early
• Avoid alcohol during treatment and for at least a day after finishing the course

Drug Interactions

Zolt Suspension can interact with several other medicines, so tell your doctor about everything you take.

• Alcohol: Causes a disulfiram like reaction with flushing, nausea and rapid heartbeat
• Warfarin: Metronidazole can increase its blood thinning effect and bleeding risk
• Lithium: Metronidazole may raise lithium levels and increase toxicity risk
• Phenobarbital or phenytoin: May reduce metronidazole's effectiveness by speeding up its breakdown

Risks and warnings

• Alcohol interaction: Drinking alcohol during or soon after treatment can cause flushing, nausea and a fast heartbeat
• Pregnancy: Use only if your doctor confirms the benefit outweighs the risk, especially in the first trimester
• Liver disease: Needs dose review since both ingredients are processed by the liver
• Blood disorders: Rare effects on blood cell counts have been reported with prolonged use
• Children: Dose must be calculated carefully by body weight under medical supervision

Zolt Suspension 250mg / 200mg Side Effects

Zolt Suspension is generally well tolerated, but some mild effects can occur.

• Nausea or stomach upset
• Metallic taste in the mouth
• Mild diarrhea or flatulence
• Loss of appetite
• Headache

Contact your doctor or seek medical help right away if you notice these serious effects.

• Severe abdominal pain or persistent vomiting
• Signs of an allergic reaction such as rash or facial swelling
• Numbness or tingling in the hands or feet
• Dark urine or yellowing of the skin and eyes

Storage Conditions

• Store below 30°C in a cool, dry place away from sunlight
• Do not refrigerate or freeze the suspension
• Keep the bottle tightly closed when not in use
• Discard any unused suspension after the labeled expiry period once opened
• Keep out of reach of children