Zyloric Tablet 300mg

Zyloric Tablet Uses

Zyloric tablet is used to decrease high uric acid levels in the blood (hyperuricemia). It can therefore help in the treatment and prevention of conditions such as gout and kidney stones. Here's how it works:

1. Treatment and prevention of gout

Zyloric (allopurinol) is used to keep blood uric acid levels below the saturation point at which monosodium urate crystals precipitate.

It reduces acute flares, extends the asymptomatic period, and gradually dissolves tophi, thereby preventing further crystal deposition in joints and soft tissue by lowering the baseline urate load. It is not an analgesic; therefore, an anti-inflammatory cover (e.g., NSAID, colchicine) is typically provided during the first 3-6 months as serum urate is being lowered.

2. Treatment and prevention of kidney stones

Zyloric (allopurinol) lowers uric acid levels in blood and urine, helping prevent kidney stone formation. It does so by inhibiting an enzyme that generates uric acid, the primary compound associated with kidney stones. The lower concentration of uric acid results in a lower potential for it to crystallize in the urine.

The medicine prevents new kidney stones from forming and helps dissolve existing stones. This mode of action reduces the risk of kidney stone formation and promotes kidney health.

3. High uric acid levels due to cancer medications

Patients undergoing radiation treatment or chemotherapy are susceptible to high uric acid levels. Zyloric can be prescribed to these patients to control uric acid levels and keep them within the normal range.

Drug Class

• Xanthine oxidase inhibitor

Dosage

Zyloric Tablet 300mg formula

• Allopurinol

Available forms

• Tablets
• Injection

Risks and warnings

1. Pregnancy and breastfeeding

In case you are pregnant or breastfeeding, take advice from your healthcare professional before taking this medication.

2. Severe allergic reactions

Some individuals may experience severe allergic reactions, including skin rash, fever, or difficulty breathing. In rare instances, a severe reaction known as Stevens-Johnson syndrome or toxic epidermal necrolysis can occur, causing significant skin damage.

3. Liver and kidney issues

Zyloric can affect liver and kidney function. It’s essential to monitor liver enzymes and kidney function, particularly for individuals with pre-existing kidney or liver disease.

4. Interaction with other drugs

Zyloric may interact with certain other medications, including anticoagulants (such as warfarin), antibiotics, and chemotherapy drugs. Inform your doctor about all the medicines you are taking.

How to use Zyloric Tablet 300mg?

• Take the medicine orally with a glass of water.
• Swallow it whole.
• Avoid crushing or chewing the tablet.
• Drink plenty of fluids when taking Zyloric.
• Take it with or without meals as prescribed.

Zyloric Tablet Side Effects

The following are the side effects of Zyloric 300mg tablets:

• Stomach ache
• Nausea
• Diarrhea
• Dizziness
• Fever
• Allergic reaction

Drug Interactions

• Aluminium hydroxide
• Captopril
• Azathioprine
• Mercaptopurine
• Warfarin
• Penicillin antibiotics

Storage Conditions

• Store the medication at room temperature.
• Store Zyloric tablets away from direct sunlight.
• Keep in a cool, dry place.
• Protect the product from moisture.
• Keep it stored away from the reach and sight of children.