About Aprovel Tablet 150mg
Aprovel 150mg contains Irbesartan, an ARB used to treat hypertension and reduce kidney damage risk in diabetics.
Aprovel Tablet 150mg Uses
- Treats high blood pressure (hypertension) in adults
- Used in type 2 diabetics with hypertension to slow kidney damage (diabetic nephropathy)
- May be combined with other blood pressure medicines for better control
- Helps lower the risk of heart attack and stroke linked to high blood pressure
Aprovel Tablet 150mg Benefits
- Once daily dosing for round the clock blood pressure control
- Protects kidney function in diabetic patients with high blood pressure
- Does not commonly cause a dry cough, unlike ACE inhibitor medicines
- Can be safely combined with a diuretic for resistant hypertension
Drug Class
- Angiotensin II receptor blocker (ARB)
What Experts Say
Irbesartan blocks the angiotensin II receptor at the AT1 subtype, preventing the vasoconstriction and aldosterone release that drive high blood pressure. This selective blockade relaxes blood vessels and reduces the strain on the heart without the dry cough commonly seen with ACE inhibitors.
Clinical trials have shown irbesartan slows the progression of diabetic kidney disease independent of its blood pressure lowering effect. Physicians often prefer it for type 2 diabetics who already show early signs of protein in the urine, since it reduces pressure inside the kidney's filtering units.
Doctors monitor potassium and kidney function periodically during treatment, since ARBs can raise potassium levels, especially when combined with potassium sparing diuretics or NSAIDs. Pakistan carries a heavy burden of undiagnosed hypertension and diabetes, making regular monitoring and adherence essential for long term protection.
Aprovel Tablet 150mg Uses in Urdu
- ہائی بلڈ پریشر کو کنٹرول کرنے کے لیے
- ذیابیطس کے مریضوں میں گردوں کو نقصان سے بچانے کے لیے
- دل کے دورے اور فالج کے خطرے کو کم کرنے کے لیے
Aprovel Tablet 150mg formula
How to use Aprovel Tablet 150mg?
- Take one tablet daily, with or without food, at the same time each day
- Swallow the tablet whole with a glass of water
- Do not stop taking it suddenly without consulting your doctor
- Your doctor may adjust the dose based on your blood pressure response
Drug Interactions
- Potassium Sparing Diuretics And Potassium Supplements: Raise the risk of high potassium levels
- NSAIDs Like Ibuprofen: Can reduce the blood pressure lowering effect and stress the kidneys
- Lithium: Irbesartan can increase lithium levels in the blood
- ACE Inhibitors Or Aliskiren: Combining raises the risk of kidney problems and high potassium
- Other Blood Pressure Medicines: May add to the blood pressure lowering effect
Risks and warnings
- Pregnancy: Avoid during pregnancy, as ARBs can cause serious harm or death to the unborn baby
- Kidney Or Liver Impairment: Use caution in patients with severe kidney or liver impairment
- Low Blood Pressure: Can cause a drop in blood pressure, especially in patients on diuretics or with low blood volume
- High Potassium: May raise blood potassium levels, particularly in kidney disease or with potassium supplements
- Renal Artery Stenosis: Not recommended in patients with bilateral renal artery stenosis
Aprovel Tablet 150mg Side Effects
- Dizziness or lightheadedness
- Fatigue or tiredness
- Headache
- Nausea
- Muscle cramps
- High potassium levels (hyperkalemia)
- Low blood pressure on standing up
- Rare allergic reactions such as rash or swelling
Storage Conditions
- Store below 30°C in a cool, dry place
- Keep the tablets in their original blister pack until ready to use
- Protect from moisture and direct sunlight
- Keep out of reach of children
