AV-Sartan Tablet 10mg / 160mg

About AV-Sartan Tablet 10mg / 160mg

AV-Sartan Tablet 10mg / 160mg Uses

• High blood pressure (hypertension)
• Blood pressure not adequately controlled on a single medicine
• Reduced risk of stroke and heart attack linked to uncontrolled hypertension
• Long term protection of the kidneys and heart from high blood pressure damage

AV-Sartan Tablet 10mg / 160mg Benefits

• Two blood pressure lowering mechanisms combined in a single tablet
• Better treatment adherence with fewer daily tablets needed
• More consistent blood pressure control than either medicine alone
• A suitable option for long term daily use under medical supervision

What Experts Say

AV-Sartan Tablet 10mg / 160mg combines Amlodipine, a calcium channel blocker, with Valsartan, an angiotensin receptor blocker. Amlodipine relaxes blood vessel walls by blocking calcium entry into smooth muscle cells, while Valsartan blocks angiotensin II, a hormone that narrows blood vessels. Together these mechanisms produce a stronger blood pressure lowering effect than either drug alone.

This fixed dose combination is generally prescribed once daily for patients whose blood pressure remains high on a single agent at maximum tolerated dose. Physicians typically monitor blood pressure, kidney function and electrolyte levels periodically, since Valsartan can affect potassium and kidney filtration in some patients. Dose adjustments are usually guided by response and tolerability rather than a fixed schedule.

Hypertension affects a very large proportion of adults in Pakistan and remains a leading contributor to heart disease, stroke and kidney failure nationwide. Physicians in Pakistan frequently turn to combination therapies like this one when lifestyle changes and single drug treatment fail to bring blood pressure to target, since combination pills also help patients stay consistent with treatment.

Drug Class

• Calcium Channel Blocker + Angiotensin Receptor Blocker (ARB) Combination

AV-Sartan Tablet 10mg / 160mg formula

• Amlodipine + Valsartan

Available forms

• Tablet

How to use AV-Sartan Tablet 10mg / 160mg?

• One tablet is taken daily, at the same time each day.
• The tablet is swallowed whole with water, with or without food.
• Sudden discontinuation is not advised, even if blood pressure feels normal.
• Regular blood pressure monitoring is recommended during treatment.
• Any plans for pregnancy should be discussed with the doctor promptly.

Drug Interactions

• Potassium Sparing Diuretics: Combined use can raise blood potassium to unsafe levels.
• NSAIDs: Regular use of painkillers like Ibuprofen can reduce the blood pressure lowering effect and affect kidney function.
• Other Blood Pressure Medicines: Combining with additional antihypertensives can cause an excessive drop in blood pressure.
• Lithium: Valsartan can increase lithium levels in the blood, raising toxicity risk.

Risks and warnings

• Pregnancy Risk: Valsartan can cause serious harm to an unborn baby, especially in the second and third trimester.
• Low Blood Pressure: Dizziness or fainting can occur, especially when starting treatment or increasing the dose.
• Kidney Function: Monitoring is required in patients with kidney artery narrowing or existing kidney disease.
• High Potassium Levels: Valsartan can raise blood potassium, particularly with certain other medicines or supplements.
• Swelling: Amlodipine can cause mild ankle or leg swelling in some patients.

AV-Sartan Tablet 10mg / 160mg Side Effects

• Ankle or leg swelling
• Dizziness or lightheadedness
• Headache
• Fatigue
• Flushing
• Low blood pressure symptoms such as fainting

Storage Conditions

• Store below 30°C in a dry place away from moisture.
• Keep the tablets in their original blister pack until ready to use.
• Keep out of reach of children.
• Do not use after the expiry date printed on the pack.