About Cinklare Suspension 100mg / 5ml
Cinklare Suspension 100mg / 5ml contains Cefixime, a cephalosporin antibiotic used for infections in children.
Cinklare Suspension 100mg / 5ml Uses
- Urinary tract infections in children
- Acute otitis media
- Pharyngitis and tonsillitis
- Acute bronchitis in children
- Typhoid fever in children
Cinklare Suspension 100mg / 5ml Benefits
- Liquid form makes accurate dosing easier for young children
- Once or twice daily dosing supports better compliance in pediatric patients
- Effective against common childhood bacterial pathogens
- Stable against many bacterial beta lactamase enzymes
- Widely trusted pediatric option for typhoid fever in Pakistan
What Experts Say
Cefixime binds to penicillin binding proteins on the bacterial cell wall, halting the final steps of cell wall synthesis so the bacterium weakens and dies. This structure keeps it stable against many bacterial beta lactamase enzymes, one reason pediatricians reach for it when a simpler antibiotic has not worked.
Dosing in children is calculated by body weight, typically around 8mg per kilogram per day. Once reconstituted with water, the suspension must be shaken well before every dose and kept refrigerated, since it can lose potency if left at room temperature too long. Pediatricians also watch for loose stools, a common but usually mild effect in young children.
Pakistan continues to see a high burden of typhoid fever in children, including strains resistant to older first line antibiotics. Oral suspensions of third generation cephalosporins like cefixime allow outpatient treatment in many uncomplicated cases. Physicians emphasize finishing the full course, since stopping early raises the risk of relapse and resistance.
Drug Class
- Third Generation Cephalosporin
- Beta Lactam Antibiotic
Cinklare Suspension 100mg / 5ml Uses in Urdu
- بچوں میں پیشاب کی نالی کے انفیکشن کے علاج میں
- بچوں میں کان کے انفیکشن میں
- گلے اور ٹانسلز کے انفیکشن میں
- بچوں میں ٹائیفائیڈ بخار کے علاج میں
- سانس کی نالی کے ہلکے بیکٹیریل انفیکشن میں
Cinklare Suspension 100mg / 5ml formula
How to use Cinklare Suspension 100mg / 5ml?
- Shake the reconstituted Cinklare Suspension well before every dose
- Measure the dose using the marked oral syringe or measuring cup provided
- Give with or without food, at the same times each day
- Store the reconstituted suspension in the refrigerator and discard any leftover after 14 days
- Complete the full prescribed course even if the child feels better sooner
Drug Interactions
- Probenecid: Raises cefixime blood levels by slowing its elimination, rarely used in children
- Carbamazepine: Cefixime can raise carbamazepine levels, increasing the risk of side effects in children treated for seizures
- Oral Typhoid Vaccine: Cefixime can reduce the effectiveness of the live oral typhoid vaccine, so spacing the two apart is advised
- Other Antibiotics: Combining with another antibiotic should only be done under a pediatrician's supervision
- Antacids: Aluminum or magnesium containing antacids may slightly affect absorption if given at the same time
Risks and warnings
- Allergy Risk: Do not give Cinklare Suspension 100mg / 5ml to a child with a known allergy to cephalosporin or penicillin antibiotics
- Kidney Impairment: Children with reduced kidney function need a lower, adjusted dose
- Severe Diarrhea: Stop the suspension and seek medical care if the child develops severe or bloody diarrhea
- Age and Weight Check: Confirm the child's age and weight based dose with a pediatrician before starting
- Prior Antibiotic Colitis: Use extra caution in children with a history of antibiotic associated colitis
- Reconstitution Care: Use only the amount of water advised by the pharmacist so each dose stays accurate
Cinklare Suspension 100mg / 5ml Side Effects
- Diarrhea
- Loose stools
- Nausea or vomiting
- Abdominal discomfort
- Skin rash
- Loss of appetite
- Diaper rash from loose stools
- Severe allergic reaction with swelling or difficulty breathing
- Severe watery or bloody diarrhea from intestinal infection
Storage Conditions
- Store the unreconstituted dry powder bottle at room temperature, below 30 degrees Celsius, away from light
- After adding water, refrigerate the reconstituted suspension between 2 and 8 degrees Celsius
- Discard any unused reconstituted suspension after 14 days
- Shake well before each use and keep the bottle tightly closed
- Keep out of reach of children
