About Corinef Suspension 100mg / 5ml
Corinef Suspension contains Cefixime, a cephalosporin antibiotic used to treat bacterial infections.
Corinef Suspension 100mg / 5ml Uses
- Bacterial infections of the throat and tonsils
- Middle ear infections in children
- Acute bronchitis and chest infections
- Urinary tract infections caused by susceptible bacteria
- Sinus infections
- Uncomplicated gonorrhea in eligible patients
Corinef Suspension 100mg / 5ml Benefits
- Once or twice daily dosing improves compliance in children
- Broad activity against common gram negative bacteria
- A stable oral option when an injectable antibiotic is not needed
- A sweet, child friendly suspension formula
- Effective against many amoxicillin resistant strains
What Experts Say
Cefixime belongs to the third generation cephalosporin group, and doctors across Pakistan value its stability against enzymes that break down older penicillins. This stability allows once or twice daily dosing to clear infections that once needed injectable antibiotics, a real advantage for young children who tolerate a liquid far better than a needle.
Physicians usually calculate the suspension dose by body weight rather than age alone, since children clear antibiotics at different rates as they grow. Careful measurement with the marked spoon or oral syringe supplied with the bottle matters, because underdosing can let resistant bacteria survive while overdosing raises the chance of stomach upset and loose stools.
Doctors also watch how a child responds over the first two to three days of treatment, since a fever that does not settle may point to a resistant organism or a viral illness that never needed an antibiotic in the first place. This habit, paired with finishing the full prescribed course, helps slow antibiotic resistance in the wider community.
Drug Class
- Third generation cephalosporin
- Beta lactam antibiotic
Corinef Suspension 100mg / 5ml Uses in Urdu
- یہ دوا بیکٹیریا کے باعث ہونے والے حلق اور ٹانسلز کے انفیکشن کے علاج کے لیے استعمال ہوتی ہے۔
- کان کے انفیکشن، خصوصاً بچوں میں، اس کے ذریعے ٹھیک کیے جاتے ہیں۔
- سینے اور سانس کی نالی کے انفیکشن میں بھی یہ مؤثر ثابت ہوتی ہے۔
- پیشاب کی نالی کے انفیکشن کے علاج میں استعمال کی جاتی ہے۔
- ناک کی ہڈیوں کے انفیکشن میں بھی ڈاکٹر کی تجویز پر دی جاتی ہے۔
Corinef Suspension 100mg / 5ml formula
How to use Corinef Suspension 100mg / 5ml?
- Shake the suspension bottle well before every dose
- Use the marked oral syringe or spoon provided for accurate dosing
- Give with or without food, though food may reduce stomach upset
- Complete the full course even if symptoms improve early
- Keep the reconstituted suspension refrigerated between doses
- Avoid mixing the dose directly into a full feeding bottle, since an incomplete feed can mean an incomplete dose
Drug Interactions
- Warfarin: Cefixime can increase the blood thinning effect of warfarin, raising bleeding risk.
- Carbamazepine: Cefixime can raise carbamazepine blood levels, increasing the chance of side effects.
- Probenecid: Probenecid slows cefixime clearance from the body and increases its blood levels.
- Oral Typhoid Vaccine: Antibiotics including cefixime can reduce the effectiveness of the live oral typhoid vaccine.
- Antacids: High dose antacids may slightly reduce cefixime absorption when taken at the same time.
Risks and warnings
- Penicillin Allergy: Cross reactivity with penicillin allergy is possible, so caution is needed in children with a history of severe penicillin reactions.
- Kidney Impairment: Dose adjustment is needed in children and adults with reduced kidney function.
- Diarrhea Risk: Cefixime carries a higher risk of loose stools than many other oral antibiotics, including rare severe colitis.
- Pseudomembranous Colitis: Persistent or bloody diarrhea during or after treatment needs prompt medical review.
- Not for Viral Infections: This antibiotic has no effect on colds, flu or other viral illnesses and should not be used for them.
Corinef Suspension 100mg / 5ml Side Effects
- Diarrhea or loose stools
- Stomach pain or cramping
- Nausea and occasional vomiting
- Loss of appetite
- Skin rash or itching
- Headache
- Dizziness
- Vaginal itching or yeast infection with prolonged use
- Severe allergic reaction with swelling of the face or throat, though rare
- Severe watery or bloody diarrhea suggesting colitis, though rare
Storage Conditions
- Store the unmixed powder bottle below 25°C in a dry place away from direct sunlight
- Refrigerate the suspension after the pharmacist reconstitutes it with water
- Discard any unused suspension 14 days after reconstitution
- Keep the bottle tightly closed and out of reach of children
- Avoid freezing the reconstituted suspension
