Dioplus Tablet 5mg / 160mg

About Dioplus Tablet 5mg / 160mg

Dioplus Tablet 5mg / 160mg Uses

• Treating high blood pressure that is not controlled by one medicine alone
• Managing hypertension in patients already using amlodipine who need added blood pressure lowering
• Reducing added strain on the heart and blood vessels from poorly controlled hypertension
• Supporting long term prevention of stroke, heart attack and kidney damage linked to high blood pressure

Dioplus Tablet 5mg / 160mg Benefits

• Combines a calcium channel blocker and an angiotensin receptor blocker in a single tablet
• Once daily dosing makes it easier to stay consistent with long term treatment
• The lower 5mg amlodipine dose can reduce the chance of ankle swelling compared to the 10mg combination
• Removes the need to take two separate blood pressure tablets each day

What Experts Say

Amlodipine belongs to the dihydropyridine class of calcium channel blockers. It relaxes smooth muscle in blood vessel walls and widens arteries, lowering the resistance the heart works against. Valsartan blocks the angiotensin II receptor, preventing a hormone that narrows vessels and raises fluid retention from acting. Combining both drugs in Dioplus Tablet 5mg / 160mg targets blood pressure through two separate pathways at once.

Doctors often prescribe this lower amlodipine strength for patients who respond well to valsartan but experience ankle swelling or flushing on the 10mg combination. Hypertension carries a heavy disease burden nationally, and many patients need more than one drug class to reach a safe target. Physicians choose the 5mg amlodipine dose to balance control against the calcium channel blocker's dose dependent side effects.

Regular blood pressure checks and periodic kidney function and electrolyte tests are advised during treatment, since valsartan can raise potassium levels in some patients. Physicians usually start at a low dose and adjust gradually rather than jumping straight to a higher strength. Consistent daily use supports long term reduction in stroke, heart attack and kidney complications linked to poorly controlled hypertension.

Drug Class

• Calcium Channel Blocker and Angiotensin II Receptor Blocker (ARB) Combination

Dioplus Tablet 5mg / 160mg formula

• Amlodipine + Valsartan

Available forms

• Tablet 5mg / 160mg

How to use Dioplus Tablet 5mg / 160mg?

• Take one tablet by mouth once daily, at the same time each day
• Swallow the tablet whole with a glass of water
• Take with or without food, but keep the timing consistent
• Do not crush or split the tablet unless your doctor directs otherwise
• Follow your doctor's guidance on dose changes; do not adjust the dose on your own

Drug Interactions

• Potassium Sparing Diuretics: Combining with spironolactone or similar drugs can raise blood potassium to unsafe levels
• Lithium: Valsartan can increase lithium levels in the blood and raise the risk of toxicity
• NSAIDs: Regular use of ibuprofen or diclofenac can reduce the blood pressure lowering effect and stress the kidneys
• Simvastatin: High dose amlodipine can raise simvastatin blood levels and the risk of muscle related side effects
• Other Blood Pressure Medicines: Combining with additional antihypertensives can increase the risk of low blood pressure
• CYP3A4 Inhibitors: Drugs such as ketoconazole or ritonavir can raise amlodipine blood levels and side effect risk

Risks and warnings

• Pregnancy: Stop the tablet as soon as pregnancy is confirmed since valsartan can cause fetal harm in the second and third trimester
• Kidney Impairment: Use with caution and monitor kidney function, since valsartan is partly cleared through the kidneys
• High Potassium: Avoid potassium supplements or salt substitutes unless your doctor approves, since valsartan can raise blood potassium
• Low Blood Pressure: Watch for dizziness or fainting, especially after the first dose or when combined with a diuretic
• Liver Impairment: Use cautiously in significant liver disease since amlodipine clearance is reduced
• Heart Failure: Use under close medical supervision since calcium channel blockers can worsen some types of heart failure

Dioplus Tablet 5mg / 160mg Side Effects

• Swelling in the ankles or feet
• Headache
• Dizziness
• Fatigue
• Flushing or warmth in the face
• Lightheadedness from low blood pressure
• Nausea
• Upper respiratory infection symptoms
• Elevated blood potassium levels
• Rare allergic reactions such as rash or swelling of the face and throat

Storage Conditions

• Store below 30 degrees Celsius in a cool dry place
• Keep the tablets in their original blister pack until use
• Protect from direct sunlight and moisture
• Keep out of reach of children
• Avoid storing in the bathroom or near a sink