About Exval-A Tablet 5mg/160mg
Exval-A Tablet 5mg/160mg combines Amlodipine and Valsartan to control high blood pressure in adults.
Exval-A Tablet 5mg/160mg Uses
- Treats high blood pressure in adults not controlled by a single medicine
- Used when two mechanisms are needed to bring blood pressure to target levels
- Reduces long term risk of stroke and heart attack linked to uncontrolled hypertension
Exval-A Tablet 5mg/160mg Benefits
- Combines two blood pressure lowering mechanisms in one tablet for better control
- May reduce the number of daily tablets needed compared to taking Amlodipine and Valsartan separately
- Helps protect the heart and kidneys by keeping blood pressure within a safer range
What Experts Say
Doctors in Pakistan prescribe Exval-A Tablet 5mg/160mg when one antihypertensive drug fails to control blood pressure. Amlodipine relaxes blood vessels by blocking calcium channels, while Valsartan blocks angiotensin II, a hormone that narrows arteries. Together they lower blood pressure through two pathways, which often works better than raising one drug's dose alone.
Hypertension affects a large share of adults in Pakistan, and many patients need combination therapy to reach recommended targets. Physicians usually start with lower strength combinations and step up to 5mg/160mg when blood pressure stays high after several weeks of monitoring, alongside regular kidney function checks.
Cardiologists caution that Exval-A Tablet should not be stopped suddenly, since blood pressure can rise again quickly. Patients with liver disease, kidney impairment, or pregnancy need close monitoring or an alternative plan. Adherence to the prescribed dose remains the most reliable way to keep blood pressure stable long term.
Drug Class
- Calcium channel blocker (Amlodipine)
- Angiotensin II receptor blocker (Valsartan)
- Fixed dose combination antihypertensive
Exval-A Tablet 5mg/160mg Uses in Urdu
- ہائی بلڈ پریشر کو کنٹرول کرنے کے لیے
- جب ایک دوا سے بلڈ پریشر کنٹرول نہ ہو رہا ہو
- دل کے دورے اور فالج کے خطرے کو کم کرنے کے لیے
Exval-A Tablet 5mg/160mg formula
How to use Exval-A Tablet 5mg/160mg?
- Take Exval-A Tablet exactly as prescribed by your doctor, usually once daily
- Swallow the tablet whole with a glass of water, with or without food
- Take it at the same time each day to maintain steady blood pressure control
- Do not stop the medicine suddenly without consulting your doctor
- Take a missed dose as soon as remembered unless the next dose is close
Drug Interactions
- Potassium Sparing Diuretics: Combined use can raise blood potassium to unsafe levels
- NSAIDs: Regular use with pain relievers like Ibuprofen or Diclofenac can reduce the blood pressure lowering effect and affect kidney function
- Lithium: Blood lithium levels can rise, increasing risk of toxicity
- Other Blood Pressure Medicines: Combining with additional antihypertensives increases the risk of low blood pressure
- CYP3A4 Inhibitors: Strong inhibitors such as Ketoconazole can increase Amlodipine levels in the blood
Risks and warnings
- Pregnancy: Can cause injury or death to an unborn baby, stop use immediately if pregnancy is confirmed
- Kidney Impairment: Use with caution and under close monitoring in patients with reduced kidney function
- Liver Disease: Dose adjustment or caution advised in patients with significant liver impairment
- Low Blood Pressure: May cause symptomatic hypotension, especially after the first dose or in volume depleted patients
- Hyperkalemia: Can raise potassium levels, particularly when combined with potassium sparing diuretics or supplements
- Angioedema: Rare but serious swelling of the face, lips, tongue or throat requires immediate medical attention
Exval-A Tablet 5mg/160mg Side Effects
- Swelling of the ankles or feet
- Headache
- Dizziness or lightheadedness
- Fatigue or tiredness
- Flushing
- Palpitations
- Low blood pressure
- Nausea
- Back pain
- Elevated potassium levels
- Allergic skin reactions
- Rare severe swelling of the face or throat (angioedema)
Storage Conditions
- Store below 30°C in a cool dry place away from direct sunlight
- Keep the tablets in their original blister pack until ready to use
- Keep out of reach of children
- Do not use after the expiry date printed on the pack
