Febrol Fast Tablet 37.5 / 325 mg

About Febrol Fast Tablet 37.5 / 325 mg

Febrol Fast Tablet Uses

• Relief from moderate to severe acute pain
• Post operative pain management
• Pain following dental procedures
• Musculoskeletal pain and injury related pain
• Pain associated with fractures or sprains

Febrol Fast Tablet Benefits

• Combines two pain relief mechanisms for faster onset
• Lower opioid dose needed compared to tramadol alone
• Reduces fever alongside pain relief
• Convenient fixed dose combination in one tablet

What Experts Say

Tramadol works on the central nervous system by binding to opioid receptors and blocking the reuptake of serotonin and norepinephrine. This dual action makes it effective for pain that does not respond well to paracetamol alone, while carrying a lower risk of severe respiratory depression than stronger opioids.

Paracetamol adds a separate analgesic and antipyretic effect by inhibiting prostaglandin synthesis in the central nervous system. Combining a lower dose of tramadol with paracetamol allows clinicians to achieve meaningful pain control while limiting the total opioid exposure and associated side effects.

Clinical experience shows this combination works best for short courses of acute pain rather than long term use, since prolonged opioid exposure raises the risk of tolerance and dependence. Careful dose monitoring is advised in older adults and patients with liver or kidney impairment.

Drug Class

• Opioid Analgesic Combination (Centrally Acting Analgesic + Non Opioid Analgesic)

Febrol Fast Tablet 37.5 / 325 mg formula

• Tramadol Hydrochloride 37.5 mg + Paracetamol (Acetaminophen) 325 mg

Available forms

• Tablet

How to use Febrol Fast Tablet 37.5 / 325 mg?

• Take this medicine exactly as prescribed by the doctor
• Swallow the tablet whole with a glass of water
• Take after meals to reduce stomach upset
• Do not exceed the maximum prescribed dose in 24 hours
• Leave at least 6 hours between two doses
• Do not stop suddenly after prolonged use without medical advice

Drug Interactions

• Selective Serotonin Reuptake Inhibitors (SSRIs): Increases risk of serotonin syndrome when combined with tramadol.
• Monoamine Oxidase Inhibitors (MAOIs): Should not be combined due to risk of severe serotonin toxicity.
• Warfarin: May enhance the anticoagulant effect and increase bleeding risk.
• Carbamazepine: Reduces tramadol effectiveness by increasing its breakdown in the liver.
• Alcohol: Increases sedation and risk of respiratory depression.
• Other Opioid Medicines: Combined use raises the risk of excessive sedation and breathing problems.

Risks and warnings

• Opioid Dependence: Prolonged use can lead to tolerance and physical dependence.
• Respiratory Depression: High doses may slow breathing, especially in elderly patients.
• Seizure Risk: Tramadol can lower the seizure threshold in susceptible individuals.
• Liver Toxicity: Paracetamol overdose can cause serious liver damage.
• Pregnancy Caution: Use only if clearly needed and under medical supervision.
• Driving Caution: May cause drowsiness and impair alertness.

Febrol Fast Tablet 37.5 / 325 mg Side Effects

• Nausea and vomiting
• Dizziness or drowsiness
• Constipation
• Dry mouth
• Headache
• Sweating
• Confusion in elderly patients
• Allergic skin reactions
• Low blood pressure
• Difficulty breathing in overdose

Storage Conditions

• Store below 30°C in a cool dry place
• Keep away from direct sunlight and moisture
• Keep out of reach of children
• Store in the original blister pack until use