About Glinext MR Tablet 60mg
Glinext MR Tablet 60mg contains Gliclazide, a sulfonylurea used to control blood sugar in type 2 diabetes.
Glinext MR Tablet 60mg Uses
- Controls high blood sugar in adults with type 2 diabetes
- Used alongside a proper diet and regular exercise when lifestyle changes alone cannot control glucose
- Sometimes combined with metformin or other antidiabetic drugs under a doctor's supervision
Glinext MR Tablet 60mg Benefits
- Provides steady blood sugar control with a single daily dose because of its modified release design
- Reduces the sharp glucose swings seen with older, immediate release sulfonylureas
- Helps lower the long term risk of diabetes complications affecting the kidneys, eyes, and nerves
- Generally easier to fit into a daily routine since it is taken only once a day with breakfast
What Experts Say
Gliclazide is a second generation sulfonylurea that lowers blood sugar by stimulating insulin release from pancreatic beta cells. The modified release formulation in Glinext MR Tablet 60mg lets the drug dissolve gradually over many hours, giving a steadier insulin response than immediate release Gliclazide taken several times a day.
Endocrinologists often prefer a modified release sulfonylurea for patients who need affordable glucose lowering without the sharp peaks and troughs of older formulations. The 60mg strength is usually reserved for patients whose sugar stays high on lower doses, since sulfonylureas carry a clear dose dependent hypoglycemia risk that rises with every step up.
Pakistan carries one of the highest burdens of type 2 diabetes in the world, and affordable oral agents such as Gliclazide remain a mainstay of treatment alongside metformin. Physicians recommend regular blood glucose monitoring and periodic kidney checks during treatment, since reduced kidney clearance can prolong the drug's effect and raise the risk of extended low blood sugar in older adults.
Drug Class
- Sulfonylurea
- Oral antidiabetic (antihyperglycemic) agent
- Second generation insulin secretagogue
Glinext MR Tablet 60mg Uses in Urdu
- ٹائپ 2 ذیابیطس میں خون میں شوگر کو قابو میں رکھنے کے لیے استعمال ہوتی ہے
- جب صرف خوراک اور ورزش سے شوگر قابو میں نہ آئے تو یہ دوا دی جاتی ہے
- بعض اوقات میٹفارمن یا دیگر ذیابیطس کی دواؤں کے ساتھ ملا کر بھی دی جاتی ہے
Glinext MR Tablet 60mg formula
How to use Glinext MR Tablet 60mg?
- Take Glinext MR Tablet 60mg once daily with breakfast, at the same time each day
- Swallow the tablet whole with a full glass of water
- Do not crush, split, or chew the tablet since this can destroy the modified release action
- Do not skip meals after taking this tablet since doing so raises the risk of low blood sugar
- Take exactly as prescribed by your doctor and do not adjust the dose on your own
Drug Interactions
- Insulin and other antidiabetic drugs: Combining these with Glinext MR raises the risk of low blood sugar and may need a dose adjustment
- Beta blockers: Can mask warning signs of low blood sugar such as a fast heartbeat
- NSAIDs such as Aspirin and Ibuprofen: May increase Gliclazide's blood sugar lowering effect and raise hypoglycemia risk
- Fluconazole and Miconazole: These antifungals can raise Gliclazide levels and increase the risk of low blood sugar
- Corticosteroids: Can raise blood sugar and reduce how well Gliclazide works
- Alcohol: Increases the risk of low blood sugar and can cause flushing or nausea
Risks and warnings
- Hypoglycemia: Can cause low blood sugar, especially if a meal is skipped, alcohol is consumed, or the dose is too high
- Sun sensitivity: Sulfonylureas can increase skin sensitivity to sunlight, so use sunscreen and protective clothing outdoors
- Elderly patients: Older adults are more prone to prolonged low blood sugar and usually need a lower starting dose with closer monitoring
- Kidney or liver impairment: Reduced clearance can raise drug levels and hypoglycemia risk, so dose adjustment or closer monitoring may be needed
- Pregnancy and breastfeeding: Not recommended since safety has not been established, and insulin is usually preferred instead
- G6PD deficiency: Sulfonylureas may trigger hemolytic anemia in patients with this enzyme deficiency
Glinext MR Tablet 60mg Side Effects
- Low blood sugar (hypoglycemia)
- Nausea or an upset stomach
- Headache
- Dizziness
- Weight gain
- Skin rash or itching
- Diarrhea or constipation
- Rare changes in liver enzymes or blood cell counts
Storage Conditions
- Store below 30°C in a cool, dry place away from direct sunlight
- Keep the tablet in its original blister pack until it is time to take it
- Do not crush, split, or repackage the tablet since this can damage its modified release coating
- Keep out of reach of children
- Do not use after the expiry date printed on the pack
