About Imdur Tablet 60mg
Imdur Tablet 60mg contains isosorbide mononitrate, a nitrate used to prevent angina attacks in heart disease.
Imdur Tablet Uses
- Prevents angina (chest pain) episodes caused by coronary artery disease
- Reduces the frequency of exertional chest pain in stable angina
- Used long term to lower the workload on the heart in ischemic heart disease
Imdur Tablet Benefits
- Widens blood vessels to improve blood flow to the heart muscle
- Lowers the heart's oxygen demand during physical activity
- Helps patients with stable angina stay active with fewer chest pain episodes
- Provides steady, once daily dosing convenience through its extended release formula
What Experts Say
Isosorbide mononitrate belongs to the organic nitrate class. It works by releasing nitric oxide inside vascular smooth muscle cells, which activates guanylate cyclase and raises cyclic GMP levels. This relaxes blood vessels, dilating veins more than arteries, and lowers the volume of blood returning to the heart.
Venous dilation lowers preload and coronary dilation improves oxygen delivery, so the heart needs less oxygen during exertion, explaining the drop in angina episodes. Clinicians usually schedule a nitrate free interval each day, since continuous exposure leads to tolerance and a gradual loss of effect.
Isosorbide mononitrate is not meant for immediate relief of an ongoing angina attack since its onset is slower than sublingual nitrates. Combining it with PDE5 inhibitors is dangerous because both drugs amplify nitric oxide mediated vasodilation, which can cause a profound and life threatening drop in blood pressure.
Drug Class
- Organic Nitrate (Antianginal Vasodilator)
Imdur Tablet 60mg Uses in Urdu
- انجائنا یعنی سینے کے درد کے حملوں کی روک تھام
- امراض قلب میں سینے کے درد کی تعدد میں کمی
- دل کی شریانوں کی بیماری میں طویل المدتی استعمال
Imdur Tablet 60mg formula
How to use Imdur Tablet 60mg?
- Take this tablet by mouth once daily in the morning, or as directed by your doctor.
- Swallow the tablet whole with water, do not crush or chew it.
- Take it at the same time every day for consistent blood levels.
- Skip a missed dose and resume the normal schedule the next day, do not double up.
- Avoid PDE5 inhibitor medicines like sildenafil while taking this tablet.
Drug Interactions
- PDE5 Inhibitors: Sildenafil, tadalafil, and vardenafil combined with this medicine can cause severe, life threatening hypotension.
- Riociguat: Concurrent use with this pulmonary hypertension drug increases the risk of dangerously low blood pressure.
- Alcohol: Drinking alcohol enhances the blood pressure lowering effect and increases dizziness.
- Antihypertensive Drugs: Combining with other blood pressure medicines can cause additive hypotension.
- Other Nitrates: Using with additional nitrate products increases the risk of excessive vasodilation and fainting.
Risks and warnings
- Severe Hypotension: Do not use with sildenafil, tadalafil, or other PDE5 inhibitors because the combination can cause dangerously low blood pressure.
- Tolerance: Continuous daily use can reduce effectiveness, doctors often prescribe a nitrate free interval each day.
- Headache: Headache is common when starting treatment and usually improves within a few days.
- Fainting Risk: Rising quickly from a sitting or lying position can cause dizziness or fainting, stand up slowly.
- Not For Acute Angina: This tablet is not fast acting and cannot relieve a sudden angina attack.
Imdur Tablet Side Effects
- Headache
- Dizziness
- Flushing of the face and neck
- Low blood pressure
- Fast heartbeat
- Nausea
- Weakness
- Fainting, especially after standing up quickly
- Skin rash in rare cases
- Severe hypotension when combined with PDE5 inhibitors
Storage Conditions
- Store below 25 degrees Celsius in a dry place away from moisture and heat.
- Keep the tablets in the original container tightly closed.
- Protect from direct sunlight and humidity.
- Keep out of reach of children.
