Maxipime injection 500mg

About Maxipime injection 500mg

Maxipime injection 500mg contains cefepime, a fourth generation cephalosporin antibiotic. Hospitals across Pakistan use it for serious bacterial infections needing intravenous treatment.

Maxipime Injection 500mg Uses

• Hospital acquired and ventilator associated pneumonia
• Complicated urinary tract infections and kidney infections
• Febrile neutropenia in cancer patients with weak immunity
• Complicated skin and soft tissue infections
• Intra abdominal infections, often alongside another antibiotic
• Serious infections in critically ill patients admitted to ICUs in Lahore, Karachi, Islamabad, and Rawalpindi

This injection targets a broad range of bacteria, including some resistant strains. A doctor decides the exact dose based on kidney function and infection severity.

Maxipime injection 500mg formula

• Cefepime

Available forms

• Injection

How to use Maxipime injection 500mg?

• This injection is given only in a hospital or clinical setting by a trained healthcare worker.
• The dose and frequency depend on the type of infection and the patient's kidney function.
• It is usually administered through a vein (IV) every 8 to 12 hours.
• The full prescribed course should be completed even if the patient feels better after a few doses.
• Patients with kidney disease need a dose adjustment, which the treating doctor calculates.

Drug Interactions

• Aminoglycosides: Combining this injection with drugs like gentamicin raises the risk of kidney damage.
• Furosemide and other loop diuretics: These can increase strain on the kidneys when combined with this antibiotic.
• Live vaccines: Effectiveness of live vaccines may be reduced during antibiotic treatment.
• Probenecid: This drug can increase blood levels of cefepime by slowing its removal from the body.
• Other nephrotoxic drugs: Combining this injection with NSAIDs or certain other medicines raises kidney strain, especially in dehydrated patients.

Risks and warnings

• Allergic reactions: People allergic to penicillin or other cephalosporins may also react to this injection.
• Seizures: High doses or reduced kidney function can raise the risk of seizures, especially in elderly patients.
• Kidney function: Dose adjustment is necessary for patients with impaired kidney function, common among Pakistan's diabetic population.
• Severe diarrhea: This antibiotic can disturb normal gut bacteria and lead to Clostridioides difficile colitis.
• Superinfection: Prolonged use may allow resistant bacteria or fungi to grow unchecked.
• Pregnancy and breastfeeding: This injection is used only when clearly needed, under direct medical supervision.

Side Effects

• Pain, redness, or swelling at the injection site
• Nausea or vomiting
• Diarrhea
• Headache
• Rash or itching
• Fever
• Seizures in rare cases, especially with high doses
• Severe allergic reaction with swelling of the face, lips, or throat
• Signs of a new infection such as unusual vaginal discharge or mouth sores
• Severe or persistent diarrhea suggesting a gut infection

Storage Conditions

Unopened vials should be stored below 25°C, away from light. Once reconstituted, the solution should be used within 24 hours if refrigerated, and any leftover solution should be discarded.