Metrox Tablet 250mg/200mg

About Metrox Tablet 250mg/200mg

Metrox Tablet 250mg/200mg Uses

• Intestinal amoebiasis (amoebic dysentery) caused by Entamoeba histolytica
• Amoebic liver abscess, used alongside other treatment
• Chronic or recurrent amoebiasis with ongoing cyst passage
• Mixed protozoal gut infections including giardiasis
• Clearing amoebic cysts after the main infection has settled

Metrox Tablet 250mg/200mg Benefits

• Targets both the active infection and the cyst stage of the amoeba in one tablet
• Lowers the chance of relapse compared to using a single antiamoebic medicine
• Combines two proven medicines into one convenient dosing schedule
• Also effective against Giardia lamblia, a common cause of traveler's diarrhea
• Widely available and affordable option for treating amoebic dysentery in Pakistan

Amoebiasis remains a common intestinal infection across Pakistan, spreading through contaminated water and street food in busy cities like Lahore, Karachi, Islamabad and Rawalpindi. Metrox Tablet 250mg/200mg is commonly prescribed here because it clears both the active infection and the resistant cysts left behind, lowering the chance of the illness returning weeks later.

The tablet combines two medicines that work at different stages of the infection. Metronidazole kills the amoeba once it invades the gut lining and bloodstream, while diloxanide furoate clears any dormant cysts still sitting in the intestine. Both together give more complete protection than either medicine alone.

Doctors usually pair this combination with a stool test before and after treatment to confirm the infection has fully cleared. The full course should be completed even after symptoms improve, since stopping early lets surviving cysts multiply again and cause a relapse.

Drug Class

• Antiamoebic combination
• Antiprotozoal
• Nitroimidazole (Metronidazole)
• Amide amoebicide (Diloxanide Furoate)

Metrox Tablet 250mg/200mg formula

• Diloxanide Furoate
• Metronidazole

Available forms

• Tablet

How to use Metrox Tablet 250mg/200mg?

• Take this tablet with or right after a meal to ease stomach upset.
• Swallow it whole with a full glass of water.
• Complete the entire course as prescribed, even if symptoms improve early.
• Space out doses evenly through the day for steady effect.
• Avoid alcohol during treatment and for at least 48 hours after the last dose.

Drug Interactions

• Alcohol: Causes a severe reaction with flushing, vomiting and a fast heartbeat.
• Warfarin: Raises bleeding risk by strengthening its blood thinning effect.
• Lithium: Metronidazole can raise lithium levels, leading to toxicity.
• Phenytoin or phenobarbital: These can lower how well this medicine works.
• Cimetidine: May raise metronidazole levels in the blood.

Risks and warnings

• Alcohol interaction: Combining this medicine with alcohol can cause flushing, vomiting and a fast heartbeat.
• Pregnancy: Avoid use in the first trimester unless a doctor confirms it is necessary.
• Liver disease: A lower dose may be needed since both ingredients are processed by the liver.
• Nerve symptoms: Numbness or tingling during a long course should be reported to a doctor right away.
• Blood counts: Extended or repeated use can lower white blood cell counts, so periodic monitoring is advised.

Side Effects

• Nausea or mild stomach upset
• Metallic taste in the mouth
• Loss of appetite
• Diarrhea or loose stools
• Flatulence and bloating
• Headache or dizziness
• Dark or reddish brown urine (harmless)
• Numbness or tingling in the hands or feet with prolonged use (rare)
• Severe allergic reaction such as rash, swelling or difficulty breathing (rare)
• Seizures or confusion with very high doses (rare)

Storage Conditions

Store below 30°C in a cool, dry place away from direct sunlight. Keep the tablet in its original strip until it is time to take it. Keep out of reach of children and discard any tablet past its printed expiry date.