Nebivol Tablet 5mg

About Nebivol Tablet 5mg

Nebivol Tablet 5mg Uses

• Treats high blood pressure (hypertension)
• Used in stable chronic heart failure in older adults
• Helps reduce cardiac workload by slowing heart rate

Nebivol Tablet 5mg Benefits

• Highly selective for beta-1 receptors, causing fewer breathing related side effects than older beta blockers
• Once daily dosing improves adherence
• Mild vasodilating effect supports blood pressure control

Drug Class

• Third generation cardioselective beta blocker

What Experts Say

Physicians across Pakistan often favor Nebivolol among beta blockers for its high beta-1 selectivity, which lowers the risk of bronchospasm compared to older non-selective agents. It also triggers nitric oxide release from vascular endothelium, adding a mild vasodilatory effect that supports blood pressure control beyond simple heart rate reduction.

Dosing typically starts at 5mg once daily for hypertension, while heart failure regimens begin lower and are titrated upward over several weeks based on tolerance. Physicians track heart rate and blood pressure closely during titration since bradycardia and hypotension are the main dose limiting effects, and slower titration is used in renal impairment.

Sudden discontinuation is avoided because withdrawing a beta blocker abruptly can trigger rebound hypertension, chest pain, or arrhythmia. Pakistan carries a significant burden of hypertension and ischemic heart disease, so adherence counseling and regular follow-up matter as much as the initial prescription for catching excessive fatigue or bradycardia early.

Nebivol Tablet 5mg formula

• Nebivolol

Available forms

• Tablet

How to use Nebivol Tablet 5mg?

• Take Nebivol Tablet 5mg once daily, at the same time each day
• Swallow the tablet whole with a glass of water
• Can be taken with or without food
• Do not stop taking suddenly without consulting your doctor
• Take a missed dose as soon as remembered unless it is near the next dose

Drug Interactions

• Calcium Channel Blockers: Combining with verapamil or diltiazem increases the risk of severe bradycardia and heart block
• Other Antihypertensives: Additive blood pressure lowering effect requires dose monitoring
• Digoxin: Increased risk of slow heart rate when used together
• Clonidine: Stopping clonidine while on a beta blocker can cause a dangerous rebound rise in blood pressure
• NSAIDs: Regular use may reduce the blood pressure lowering effect of Nebivolol

Risks and warnings

• Heart Block: Avoid use in patients with severe sinus node dysfunction or high grade AV block without a pacemaker
• Severe Liver Disease: Not recommended in severe hepatic impairment due to limited safety data
• Asthma And COPD: Use with caution since beta blockers can still trigger bronchospasm in sensitive patients
• Abrupt Withdrawal: Stopping suddenly can worsen angina or trigger rebound high blood pressure
• Pregnancy And Breastfeeding: Use only if clearly needed and under medical supervision

Nebivol Tablet 5mg Side Effects

• Headache
• Fatigue or tiredness
• Dizziness
• Slow heart rate (bradycardia)
• Low blood pressure
• Swelling in the ankles or feet
• Nausea
• Diarrhea
• Shortness of breath in sensitive patients

Storage Conditions

• Store at room temperature, below 30°C
• Keep away from direct sunlight and moisture
• Store in the original blister pack until ready to use
• Keep out of reach of children