About Paromax CR Tablet 25mg
Paromax CR Tablet 25mg contains Paroxetine, an SSRI used to treat depression and anxiety disorders.
Paromax CR Tablet 25mg Uses
- Major depressive disorder
- Panic disorder with or without agoraphobia
- Generalized anxiety disorder
- Social anxiety disorder
- Premenstrual dysphoric disorder
Paromax CR Tablet 25mg Benefits
- Once daily dosing helps maintain steady mood control through the day
- Controlled release formulation lowers early nausea compared to immediate release paroxetine
- Eases both emotional and physical symptoms of anxiety
- Improves sleep and appetite disturbances linked to depression
- Reduces the frequency and intensity of panic attacks over time
What Experts Say
Paroxetine works by blocking serotonin reuptake in the brain, gradually raising serotonin levels at nerve synapses. The controlled release formulation delays absorption in the gut, which physicians recommend because it lowers early nausea compared with immediate release tablets while keeping the same total daily dose.
Doctors across Pakistan generally start therapy at a low dose and review response after four to six weeks, since the full antidepressant effect builds slowly. Older patients and those with liver impairment need closer monitoring because paroxetine clearance slows with age and reduced hepatic function.
Physicians recommend tapering the dose gradually rather than stopping suddenly, because paroxetine has a short half life and abrupt withdrawal often triggers dizziness, irritability and flu like symptoms. Combining it with other serotonergic drugs is avoided due to serotonin syndrome risk.
Drug Class
- Selective Serotonin Reuptake Inhibitor (SSRI)
- Antidepressant
- Anxiolytic agent
Paromax CR Tablet 25mg Uses in Urdu
- ذہنی دباؤ یعنی ڈپریشن کے علاج کے لیے استعمال ہوتی ہے۔
- گھبراہٹ اور پینک اٹیک کو کم کرنے میں مدد دیتی ہے۔
- عمومی بے چینی یعنی اینزائٹی کی شدت کم کرتی ہے۔
- سماجی خوف اور جھجک کے علاج میں مؤثر ہے۔
- ماہواری سے پہلے ہونے والی شدید ذہنی بے چینی میں تجویز کی جاتی ہے۔
Paromax CR Tablet 25mg formula
How to use Paromax CR Tablet 25mg?
- Take one tablet by mouth once daily, preferably in the morning with food
- Swallow the tablet whole; do not crush, chew or split the controlled release tablet
- Take it at the same time each day to keep blood levels steady
- Do not stop the medicine suddenly; the dose should be reduced gradually under medical advice
- If a dose is missed, take it as soon as remembered unless the next dose is nearly due
Drug Interactions
- MAOIs: Combination can cause a potentially fatal serotonin reaction; avoid within 14 days of MAOI use
- NSAIDs and Aspirin: Increased risk of gastrointestinal bleeding when combined with paroxetine
- Tamoxifen: Paroxetine inhibits the enzyme that activates tamoxifen, potentially reducing its effectiveness in breast cancer treatment
- Other Serotonergic Drugs: Triptans, tramadol and other SSRIs raise the risk of serotonin syndrome
- Warfarin: May increase bleeding risk when used alongside paroxetine
- Alcohol: Increases sedation and impairs mental alertness when combined with paroxetine
Risks and warnings
- Suicidal Thoughts: Young adults and adolescents may experience increased suicidal thinking during early treatment, so close monitoring is advised
- Discontinuation Syndrome: Sudden stoppage can cause dizziness, irritability, electric shock sensations and flu like symptoms
- Pregnancy Risk: Use in late pregnancy has been linked to neonatal complications and should only continue under specialist guidance
- Serotonin Syndrome: Combining with other serotonergic medicines can cause a dangerous rise in serotonin levels
- Bleeding Risk: Concurrent use with aspirin or NSAIDs raises the risk of gastrointestinal bleeding
- MAOI Contraindication: Must not be taken within two weeks of stopping a monoamine oxidase inhibitor due to risk of a severe reaction
Paromax CR Tablet 25mg Side Effects
- Nausea
- Drowsiness or sedation
- Dry mouth
- Excessive sweating
- Decreased appetite
- Sexual dysfunction including reduced libido and delayed ejaculation
- Weight gain with long term use
- Tremor
- Blurred vision
- Constipation or diarrhea
- Insomnia or vivid dreams
- Headache
Storage Conditions
- Store below 30°C in a cool, dry place away from direct sunlight
- Keep the tablets in their original blister strip until ready to use
- Keep out of reach of children
- Do not store in the bathroom or in a humid place
