Paroxin CR Tablet 12.5mg

About Paroxin CR Tablet 12.5mg

Paroxin CR Tablet 12.5mg Uses

• Major depressive disorder
• Generalized anxiety disorder
• Panic disorder with or without agoraphobia
• Social anxiety disorder
• Obsessive-compulsive disorder (OCD)
• Post-traumatic stress disorder (PTSD)

Paroxin CR Tablet 12.5mg Benefits

• Controlled-release formula releases the drug gradually, reducing peak-level side effects
• Once-daily dosing supports long-term treatment adherence
• Effective for both depressive and multiple anxiety-spectrum conditions
• Non-habit-forming compared to older anti-anxiety medicines like benzodiazepines

What Experts Say

Psychiatrists often choose the controlled-release form of paroxetine over the immediate-release version because the gradual release smooths out blood levels across the day, which tends to reduce nausea and other early gastrointestinal side effects that make some patients stop treatment too soon.

Paroxetine works by blocking the reabsorption of serotonin in the brain, increasing its availability at nerve synapses. Full antidepressant effect typically takes two to six weeks to develop, so doctors counsel patients not to expect immediate relief and not to stop the medicine abruptly once it starts working.

Sudden discontinuation of paroxetine is more likely to cause withdrawal symptoms than most other SSRIs, since it has a comparatively short half-life. Physicians manage this by tapering the dose gradually over several weeks, an approach that meaningfully reduces dizziness, irritability and sensory disturbances during withdrawal.

Drug Class

• Selective serotonin reuptake inhibitor (SSRI)

Paroxin CR Tablet 12.5mg formula

• Paroxetine

Available forms

• Tablet

How to use Paroxin CR Tablet 12.5mg?

• This tablet is usually taken once daily, in the morning, exactly as prescribed
• The tablet should be swallowed whole and not crushed or chewed
• It can be taken with or without food at a consistent time each day
• This medicine should not be stopped suddenly without a doctor's advice
• A missed dose should not be doubled up the next day

Drug Interactions

• Monoamine Oxidase Inhibitors (MAOIs): This combination can cause dangerous serotonin syndrome.
• Tramadol and Other Serotonergic Drugs: The risk of serotonin syndrome increases with combined use.
• NSAIDs and Aspirin: The risk of gastrointestinal bleeding increases with combined use.
• Warfarin: Bleeding risk can increase when combined with paroxetine.
• Tamoxifen: Paroxetine can reduce tamoxifen's effectiveness by blocking its conversion to its active form.

Risks and warnings

• Suicidal Thoughts: Worsening mood or new suicidal thoughts need close attention, especially in young adults during early treatment.
• Withdrawal Symptoms: Abrupt stopping can cause dizziness, irritability and sensory disturbances.
• Serotonin Syndrome: The risk increases when combined with other serotonergic medicines.
• Pregnancy: First-trimester use has been linked to a small increase in birth defect risk, so alternatives should be discussed with a doctor.
• Bleeding Risk: Combined use with NSAIDs or blood thinners can raise bleeding tendency.

Paroxin CR Tablet 12.5mg Side Effects

• Nausea
• Dry mouth
• Drowsiness or fatigue
• Insomnia
• Sexual dysfunction
• Sweating
• Constipation
• Weight changes
• Dizziness
• Tremors

Storage Conditions

• Store below 30°C in a dry place away from moisture
• Keep the tablets in their original blister pack until use
• Protect from direct sunlight and heat
• Keep out of reach of children