Secure Capsule 400mg

About Secure Capsule 400mg

Secure Capsule Uses

• Typhoid fever caused by susceptible Salmonella strains
• Urinary tract infections
• Throat and tonsil infections such as streptococcal pharyngitis
• Middle ear infections
• Uncomplicated respiratory tract infections caused by susceptible bacteria

Secure Capsule Benefits

• Once daily dosing convenience for a full treatment course
• Strong activity against common typhoid causing bacteria
• Suitable oral alternative when injectable antibiotics are not required
• Good safety profile with a low rate of serious side effects

What Experts Say

Cefixime is a third generation cephalosporin antibiotic. It works by blocking the formation of the bacterial cell wall, which weakens the bacteria and eventually causes them to die off during treatment.

Doctors commonly choose it for typhoid fever and urinary infections because it reaches effective levels in blood and urine with once daily oral dosing, which is easier for patients to complete compared to multiple daily doses.

Typhoid fever remains a significant public health concern in Pakistan, particularly in areas with unreliable clean water supply. Rising resistance to older antibiotics, including extensively drug resistant typhoid strains reported in parts of the country, has made cefixime based capsules like this one a frequently prescribed option for confirmed or suspected typhoid cases. Blood culture confirmation is generally recommended before starting a full course whenever it is practical.

Drug Class

• Third generation cephalosporin antibiotic

Secure Capsule 400mg formula

• Cefixime

Available forms

• Capsule

How to use Secure Capsule 400mg?

• Take this capsule at the same time each day, with or without food.
• Swallow the capsule whole with a glass of water.
• Complete the entire prescribed course even if symptoms improve early.
• Avoid missing doses to reduce the risk of antibiotic resistance.

Drug Interactions

• Warfarin: This capsule can increase the blood thinning effect of warfarin and raise bleeding risk.
• Probenecid: This medicine raises blood levels of cefixime by slowing its removal from the body.
• Oral typhoid vaccine: This live vaccine should not be given during or shortly after this antibiotic course because it can reduce vaccine effectiveness.

Risks and warnings

• Penicillin allergy: People with a severe penicillin allergy may also react to this cephalosporin antibiotic due to cross sensitivity.
• Clostridioides difficile diarrhea: Severe or persistent diarrhea during or after this capsule can signal a serious intestinal infection that needs prompt medical attention.
• Kidney impairment: A lower dose or extended interval is needed in people with reduced kidney function.
• Incomplete treatment: Stopping the course early can allow bacteria to survive and become resistant to future treatment.

Secure Capsule Side Effects

• Diarrhea
• Nausea
• Abdominal pain
• Headache
• Skin rash
• Loss of appetite

Storage Conditions

• Store below 30°C in a dry place.
• Protect the capsules from moisture and direct light.
• Keep the strip sealed until the capsule is needed.
• Keep out of reach of children.