TreviaMet tablet 50mg / 1000mg

About TreviaMet tablet 50mg / 1000mg

TreviaMet Tablet 50mg/1000mg Uses

• Type 2 diabetes in adults, with diet and exercise
• When sitagliptin or metformin alone does not control sugar
• Replacement for the two separate tablets in patients already taking both
• Adults whose HbA1c stays high on a single diabetes medicine

TreviaMet Tablet 50mg/1000mg Benefits

• Two medicines with different actions in one tablet
• Fewer tablets to take, which helps regular use
• Low risk of low blood sugar when not used with insulin or sulfonylureas
• Helps improve HbA1c levels

What Experts Say

TreviaMet combines sitagliptin and metformin. Sitagliptin helps the pancreas release insulin after meals. Metformin reduces sugar made by the liver and helps the body respond better to insulin. It is prescribed as a fixed combination only after each ingredient has been tolerated or when the patient already takes both.

Using two medicines with different actions often gives better control than either alone. The fixed combination also means fewer tablets to remember. Regular blood tests for kidney function and HbA1c guide the dose over time.

Metformin can rarely cause a serious build up of lactic acid, mostly in people with kidney problems, heavy alcohol use or severe illness. Doctors check kidney function before and during treatment and may pause it before surgery or scans with contrast dye. Report vomiting, dehydration or any illness that stops normal eating and drinking, since the tablet may need to be paused.

Drug Class

• Antidiabetic combination (DPP-4 inhibitor and biguanide)

TreviaMet tablet 50mg / 1000mg formula

• Sitagliptin
• Metformin

Available forms

• Tablet

How to use TreviaMet tablet 50mg / 1000mg?

• Take TreviaMet tablet twice daily with meals, as prescribed, to lower stomach upset.
• Swallow the tablet whole with water.
• Avoid alcohol, since it raises the risk of lactic acidosis.
• Keep up diet, exercise and regular blood sugar checks.

Drug Interactions

• Insulin and sulfonylureas: Combined use can cause low blood sugar, so those doses may need to be reduced.
• Alcohol: Heavy drinking increases the risk of lactic acidosis and low blood sugar.
• Iodinated contrast dye: It can affect the kidneys, so the tablet may need to be stopped before and after the scan.

Risks and warnings

• Lactic acidosis: A rare but serious problem linked to metformin, causing weakness, fast breathing and stomach pain, which needs urgent care.
• Kidney and liver disease: It should not be used in significant kidney impairment, and liver disease needs caution.
• Pancreatitis: Severe stomach pain that reaches the back needs urgent review and stopping the tablet.
• Contrast dye and surgery: It may need to be paused before scans with contrast dye or surgery.
• Vitamin B12: Long term use can lower B12, so periodic checks may be advised.

TreviaMet Tablet 50mg/1000mg Side Effects

• Nausea or vomiting
• Diarrhea or loose stools
• Stomach pain or bloating
• Metallic taste
• Headache
• Stuffy nose or sore throat
• Low blood sugar when used with insulin or a sulfonylurea

Storage Conditions

• Store below 30 degrees Celsius.
• Protect from sunlight and moisture.
• Keep out of reach of children.