About Voltral Suppositories 100mg
Rectal suppository form of Diclofenac Sodium for short term relief of moderate pain and inflammation.
Voltral Suppository Uses
- Postoperative pain and swelling
- Acute musculoskeletal pain including back pain and sprains
- Osteoarthritis and rheumatoid arthritis pain flares
- Ankylosing spondylitis pain and stiffness
- Acute gout attacks
- Menstrual cramps and pelvic pain
- Fever and pain when oral medicines cannot be taken
Voltral Suppository Benefits
- Bypasses the stomach so it suits patients who cannot swallow tablets or who have nausea and vomiting
- Delivers steady drug levels for sustained pain and inflammation control
- Works well overnight since it is often dosed at bedtime
- Useful after minor day care surgery when oral intake is restricted
- Reduces swelling alongside pain in joint and soft tissue conditions
What Experts Say
Diclofenac sodium is a nonsteroidal anti-inflammatory drug that blocks cyclooxygenase enzymes, lowering prostaglandin production at the site of injury. This action reduces pain signaling and the swelling that follows tissue damage or joint inflammation. The rectal route allows the drug to enter circulation without first passing through the stomach lining.
Clinicians often prefer the suppository form for patients recovering from surgery who face nausea or cannot take oral medicine safely. It also suits patients with swallowing difficulty or those who need pain relief through the night without waking to take a tablet. Absorption through the rectal mucosa is generally reliable, though it can vary slightly between patients.
Despite the different entry route, diclofenac suppositories carry the same systemic NSAID risks as tablets, including gastrointestinal, kidney and cardiovascular effects. Experts recommend the lowest effective dose for the shortest duration needed, with closer monitoring in older adults and those with existing heart, kidney or liver conditions.
Drug Class
- Nonsteroidal Anti Inflammatory Drug (NSAID)
- Phenylacetic Acid Derivative
Voltral Suppositories 100mg Uses in Urdu
- آپریشن کے بعد ہونے والے درد اور سوزش میں
- جوڑوں کے درد اور اوسٹیوآرتھرائٹس میں
- ریمیٹائیڈ آرتھرائٹس کی سوزش میں
- گاؤٹ کے شدید دورے میں
- ماہواری کے درد اور مروڑ میں
- کمر درد اور موچ میں
- بخار میں جب دوا منہ کے ذریعے لینا ممکن نہ ہو
Voltral Suppositories 100mg formula
How to use Voltral Suppositories 100mg?
- Empty the bowel and bladder before inserting the suppository if possible
- Wash hands thoroughly before and after use
- Remove the suppository from its wrapper and moisten the tip with water if it feels dry
- Lie on one side with the lower leg straight and the upper leg bent toward the chest
- Gently insert the suppository pointed end first into the rectum using a finger, pushing it about an inch past the sphincter
- Stay lying down for a few minutes so the suppository does not slip out
- Use one suppository at a time as directed by the doctor, usually once or twice daily
- Do not use with oral or topical Diclofenac products at the same time unless a doctor advises it
- Avoid using for longer than prescribed without medical review
Drug Interactions
- Aspirin and Other NSAIDs: Combined use raises the risk of gastrointestinal bleeding and reduces the cardioprotective effect of low dose aspirin
- Warfarin and Anticoagulants: Diclofenac increases bleeding risk when taken with blood thinners
- ACE Inhibitors and ARBs: Diclofenac can reduce the blood pressure lowering effect and worsen kidney function when combined with these medicines
- Diuretics: Effectiveness of diuretics may be reduced and kidney strain can increase with concurrent use
- Methotrexate: Diclofenac can raise Methotrexate levels in the blood, increasing toxicity risk
- Lithium: NSAIDs can raise Lithium levels, requiring closer monitoring
- Corticosteroids: Combined use further increases the risk of gastrointestinal ulcers and bleeding
- SSRIs: Selective serotonin reuptake inhibitors combined with Diclofenac raise the risk of gastrointestinal bleeding
Risks and warnings
- Gastrointestinal Bleeding: NSAIDs including Diclofenac can cause stomach ulcers, bleeding or perforation, sometimes without warning symptoms, especially with long term use
- Cardiovascular Risk: Diclofenac carries an increased risk of heart attack and stroke, which rises with higher doses and longer duration of use
- Kidney Function: NSAIDs can reduce blood flow to the kidneys and worsen kidney function, particularly in dehydrated patients or those with existing kidney disease
- Rectal Irritation: The suppository can cause local irritation, burning or mucosal inflammation at the insertion site in some patients
- Liver Effects: Rare cases of elevated liver enzymes or liver injury have been reported with Diclofenac use
- Pregnancy Caution: Use in the third trimester of pregnancy is generally avoided due to risks to the unborn baby
- Rectal Bleeding History: Patients with recent rectal surgery, bleeding hemorrhoids or proctitis should avoid this form unless a doctor approves it
Voltral Suppository Side Effects
- Rectal irritation or burning sensation
- Stomach pain or indigestion
- Nausea or vomiting
- Diarrhea or constipation
- Headache or dizziness
- Mild rectal bleeding or mucus discharge
- Fluid retention or swelling in the ankles
- Elevated blood pressure
- Signs of stomach bleeding such as black stools or vomiting blood
- Sudden chest pain, shortness of breath or slurred speech
- Severe allergic reaction with facial swelling or difficulty breathing
- Marked decrease in urine output
Storage Conditions
- Store below 25 degrees Celsius in a cool, dry place away from direct sunlight
- Keep suppositories in their original strip until ready to use
- Refrigerate if the suppositories feel soft or the room is very hot, as heat can cause them to melt
- Keep out of reach of children
- Do not use if the suppository appears melted, cracked or discolored
- Dispose of expired or unused suppositories safely, not in household drains