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Leflox Tablet Uses, Side Effects & Price in Pakistan

Dr. Arslan Shamim

4 min read

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Leflox is a common antibiotic. When you get an infection, your healthcare provider may prescribe you an antibiotic to treat your condition. There are various antibiotics and your healthcare provider will prescribe the one that best suits your needs. Leflox is a familiar antibiotic that is often prescribed to treat infections.

Below we will tell you the essential information regarding Leflox including leflox tablet uses, side effects, price in Pakistan and more so keep reading.

What is Leflox?

Leflox is an antibiotic that belongs to a quinolone group of antibiotics. It works by stopping the growth of bacteria. Quinolones are most commonly given to treat bacterial infections.

Leflox tablet uses

Leflox tablet uses can be summarized as follows:

  • Urinary tract infection
  • Sinusitis
  • Otitis media
  • Upper respiratory tract infection 
  • Lower respiratory tract infection
  • Community-acquired pneumonia 
  • Salmonellosis 
  • Infections of the oral cavity
  • Lyme disease
  • Prophylaxis for anthrax exposure
  • Meningitis 
  • Endocarditis
  • H. Pylori infection
  • Skin infections 
  • Typhoid fever 
  • Parathyroid fever
  • Prosthetic joints infection 
  • Tonsillitis 
  • Pharyngitis 
  • Cystitis 
  • Urethritis 
  • Impetigo 
  • Cellulitis 
  • Furunculosis 
  • Prosthetic joints infection 
  • Prevention of secondary cases of invasive group A streptococcal infection
  • Uncomplicated genital chlamydial infections
  • Nongonococcal urethritis
  • Uncomplicated gonorrhea

How to take Leflox?

You can take Leflox with or without food. But try to take it with food if taken by mouth as it may upset your stomach or cause gastric ulcers when taken on an empty stomach. Tell your doctor if you feel stomach pain or nausea, as it may be a sign of gastritis. Do not crush or chew the capsule or tablet.

You should take a Leflox tablet with a glass of water. Swallow it whole. Follow the dose and frequency as advised by the doctor. Do not alter them, as it can lead to other problems. 

Before stopping its use, you must consult with a healthcare provider.

Lefolox dosage and strengths

Leflox is available as:

  • Tablet as 250mg, 500 and 750mg
  • Oral solution as 25mg/ml
  • Injection as 500mg/20ml and 750mg/30ml
  • Premixed ready to use injections as 250 mg/50 ml, 500 mg/100 ml, and 750 mg/150 ml

The dose of Leflox for an adult is 250mg to 750mg, depending on the severity of the infection. The dosage of Leflox for throat infection and Leflox for prostatitis is 500mg once daily. 

What are the side effects of Leflox?

Leflox tablet side effects are

  • Abdominal pain 
  • Vomit containing coffee grounds 
  • Blood in stool 
  • Constipation 
  • Black stools 
  • Acid reflux
  • Anemia 
  • Elevation of liver enzymes
  • Diarrhea 
  • Serum sickness 
  • Crystalluria
  • Tendinitis 

Leflox formula

Leflox contains the generic Levofloxacin hemihydrate, which belongs to the quinolone group of antibiotics. 

What are the alternatives to Leflox?

You can find the brands of Levofloxacin tablets by the names of 

  • Leflox
  • Levo
  • Bexus 

What are the available forms of Leflox?

Leflox is available as a tablet, oral solution, injection, and premixed ready-to-use injection. 

How is Leflox classified?

Leflox is an antibiotic that belongs to the quinolones group of antibiotics. It works by stopping the growth of bacteria. They are only active against bacteria. Therefore, they are only indicated for the treatment of bacterial infection.

What are the risks and warnings for Leflox?

Following are the risks and warnings of Leflox:

1. Allergic to Leflox

If you are allergic to Levofloxacin, do not take Leflox or any other medicine with the same generic name, as it can result in a life-threatening condition called anaphylactic shock. Always inform your healthcare provider about the documented allergies you have. 

Anaphylactic shock is a rare but severe allergic reaction. If not treated at the right time, it can be life-threatening. The signs and symptoms of an anaphylaxis reaction are hives, pale skin, labored breathing, itching, excessive salivation, feeling too warm, a weak and rapid pulse, nausea, vomiting, runny nose, sneezing, swollen lips and tongue, wheezing, dizziness, low blood pressure, and tingling hands, feet, mouth, or scalp.

2. Non-susceptible organisms

Leflox should be given to the patient only when the bacteria are sensitive to it. If not, it can lead to antibiotic resistance, making it difficult to treat infections next time. It mostly applies to urinary tract infections and infections of the nose, ear, and throat.

3. Diarrhea 

Leflox can cause diarrhea. It occurs because, in our digestive tract, healthy bacteria are present that help in digestion. During the antibiotic course, these healthy bacteria are also killed, leading to adverse gastrointestinal effects like diarrhea. Therefore, if you have a complaint of stomach upset, you must report it to your healthcare provider.

4. Tendinitis 

If you have any disease or inflammation of tendons, you must not take Leflox as it may exacerbate the condition. 

5. Peripheral neuropathy 

Leflox can cause peripheral neuropathy. Therefore, avoid its use if you already have the same condition. If you have the same complaint, you must tell your healthcare provider about it. 

6. Muscle weakness or Myasthenia Gravis

If you have any disease that causes muscle weakness, like myasthenia gravis, you must not take Leflox, as quinolones can worsen the condition. 

7. Seizures 

If you have had a history of seizures or you have renal impairment, you must avoid the use of Leflox as it can provoke seizures. Also, if you have conditions that can cause seizures like a brain tumor, brain injury, or cerebral atherosclerosis, you must take Leflox with caution. You must inform your health care provider about your complete health condition.

8. Kidney failure 

If your kidneys do not work well, the healthcare provider may lower the dose of the drug. It happens because your kidneys are meant to excrete out the waste and toxins. If that does not happen, the toxins may build up in your body, leading to severe adverse effects. Therefore, you must inform your health care provider about your complete health condition.

9. Gastric ulcers

People suffering from gastric ulcers and acidity must take Leflox with extreme caution because it affects your gastrointestinal tract. 

Also, it can cause ulceration in your stomach lining when taken for the long term. Your doctor may prescribe a gastroprotective agent along with it.

10. Liver diseases

Patients with liver disease should take Leflox with caution. It is because your liver helps in the metabolism and excretion of drugs. When it does not work efficiently due to any disease, it can cause an accumulation of the drug in your body, leading to severe adverse effects. 

11. Heart diseases and hypertension 

If you have a history of heart disease, heart attack, or hypertension, you must take Leflox with caution as it can worsen the preexisting condition.

12. Mental disorders

If you have any mental disorders like depression and anxiety, you must take Leflox with caution as it can worsen the preexisting condition. Always tell your healthcare provider about the health conditions you have. 

13. Blood vessels diseases

If you have any disease of the blood vessels like atherosclerosis or aneurysms, you must take Leflox with caution. 

14. Marfan syndrome 

If you have Marfan syndrome, take Leflox with caution. Always inform your healthcare provider about it as it can worsen the condition.

15. Arrhythmias

If you have a history of arrhythmias (a condition in which the rhythm of the heart gets abnormal) take Leflox with caution because it can cause QT interval prolongation of the heart. It is a life-threatening condition. 

16. Pregnancy and breastfeeding

If you are pregnant, do not take Leflox unless your doctor advises it. It can affect your baby’s health. Breastfeeding mothers should also consult with a healthcare provider before taking it. Generally, they are not given during pregnancy and breastfeeding because of their adverse effects on the baby. 

Interaction between Leflox and other medicines

Leflox is a quinolone antibiotic. It may interact with the following drugs. A drug interaction does not mean that you stop taking the medicine on your own. But you must tell your healthcare provider about it. 

  • Probenecid
  • Blood thinners like warfarin 
  • Allopurinol 
  • Oral birth control pills containing estrogen and progesterone.
  • Other antibiotics like chloramphenicol, tetracyclines, sulfonamides, and macrolides.
  • Opioid drugs 
  • Drugs that affect heart rhythms like procainamide, amiodarone, quinidine, sotalol, and dofetilide.

To avoid drug interactions, you must give a complete history to the healthcare provider about other health conditions you have and what medicines you have been taking. At times, a dose adjustment can help prevent drug interaction. 

Leflox Tablet Price in Pakistan

The price of Leflox in Pakistan in the year 2022 is Rs. 31.82 per tablet approximately.

Storage Conditions

  • Keep the product out of the reach and sight of children. 
  • Store it at room temperature.
  • Do not use it after the mentioned expiry date.
  • Protect it from direct heat and sunlight.

Do you Need a Prescription to Buy Leflox?

For buying Levofloxacin, you will require to have the prescription signed by your doctor. 

Disclaimer: The contents of this article are intended to raise awareness about common health issues and should not be viewed as sound medical advice for your specific condition. You should always consult with a licensed medical practitioner prior to following any suggestions outlined in this article or adopting any treatment protocol based on the contents of this article.

Dr. Arslan Shamim - Author Dr. Arslan Shamim is a highly qualified Internal Medicine Specialist with a number of certifications including M.B.B.S, F.C.P.S (Medicine) and M.R.C.P. -II (UK) as well as 9 years of experience in his field and He is also a highly skilled Family Physician.
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