About Amper Tablet 4mg / 5mg
Amper Tablet 4mg / 5mg combines perindopril and amlodipine to treat high blood pressure and angina.
Amper Tablet Uses
- Treats high blood pressure
- Prevents and treats angina, chest pain caused by reduced blood flow to the heart
- Reduces the risk of heart attack and stroke in people with stable coronary artery disease
- Used as add-on therapy when a single blood pressure medicine is not enough
Amper Tablet Benefits
- Combines two complementary mechanisms for stronger blood pressure control
- Once daily dosing improves convenience and adherence
- Lower dose of each drug reduces the risk of side effects seen with higher single drug doses
- Helps protect the heart and blood vessels over the long term
- Suitable for long term management of chronic hypertension
What Experts Say
Doctors combine perindopril and amlodipine in one tablet because each drug lowers blood pressure through a different pathway. Perindopril relaxes blood vessels by blocking the enzyme that produces angiotensin II, while amlodipine relaxes vessel walls by blocking calcium entry into muscle cells. Together they produce a stronger, steadier effect than either drug alone at a comparable dose.
Pakistan has one of the highest rates of hypertension in South Asia, and many patients need more than one medicine to reach their target blood pressure. Physicians often move to a fixed dose combination like Amper Tablet 4mg / 5mg once a single ACE inhibitor or calcium channel blocker alone fails to control pressure, since one tablet also improves how consistently patients take their medicine.
Clinicians monitor kidney function, potassium levels and blood pressure response after starting or adjusting the dose, particularly in older adults or anyone with existing kidney disease. Swelling in the ankles and a persistent dry cough are the most commonly discussed side effects, and either one is usually a reason to review the treatment plan with a doctor.
Drug Class
- ACE Inhibitor (Perindopril)
- Calcium Channel Blocker (Amlodipine)
Amper Tablet 4mg / 5mg Uses in Urdu
- ہائی بلڈ پریشر کے علاج میں
- انجائنا یعنی سینے کے درد میں
- دل کے دورے اور فالج کے خطرے کو کم کرنے میں
- جب ایک دوا سے بلڈ پریشر قابو میں نہ آئے تو اضافی علاج کے طور پر
Amper Tablet 4mg / 5mg formula
How to use Amper Tablet 4mg / 5mg?
- Take one tablet daily, preferably in the morning, with or without food.
- Swallow the tablet whole with a glass of water.
- Take it at the same time each day for consistent blood pressure control.
- Do not stop taking it suddenly without consulting a doctor.
- Missed doses should be taken as soon as remembered unless the next dose is close.
Drug Interactions
- Potassium-Sparing Diuretics: Combined use with perindopril can raise potassium to dangerous levels.
- NSAIDs: Regular use of painkillers like ibuprofen or diclofenac can reduce the blood pressure lowering effect and stress the kidneys.
- Other Blood Pressure Medicines: Can add to the blood pressure lowering effect, increasing the risk of low blood pressure.
- Lithium: Perindopril can raise lithium levels, increasing the risk of toxicity.
- Simvastatin: High dose simvastatin combined with amlodipine can increase the risk of muscle related side effects.
Risks and warnings
- Low Blood Pressure: Can cause dizziness or fainting, especially after the first dose or in people who are dehydrated.
- Kidney Function Changes: May raise creatinine or affect kidney function, particularly in people with existing kidney disease.
- High Potassium Levels: Perindopril can raise blood potassium, which needs monitoring in people with kidney problems or on potassium supplements.
- Pregnancy: Not recommended during pregnancy, as ACE inhibitors can harm the developing baby.
- Swelling: Amlodipine can cause ankle or leg swelling, particularly at higher doses.
Amper Tablet Side Effects
- Dizziness
- Headache
- Dry cough
- Ankle or leg swelling
- Fatigue
- Flushing
- Palpitations
- Lightheadedness on standing due to low blood pressure
- Signs of angioedema such as swelling of face, lips, tongue or throat, needs urgent care
Storage Conditions
- Store below 30°C in a cool, dry place away from direct sunlight and moisture.
- Keep the tablets in their original blister pack until use.
- Keep out of reach of children.
- Do not use beyond the expiry date printed on the pack.
