Fixim Capsule 400mg

About Fixim Capsule 400mg

Fixim Capsule 400mg Uses

• Treats respiratory tract infections like bronchitis and tonsillitis
• Clears urinary tract infections caused by susceptible bacteria
• Manages typhoid fever caused by Salmonella typhi
• Treats acute middle ear infections in children and adults

Fixim Capsule 400mg Benefits

• Works against a broad range of gram negative and gram positive bacteria
• Requires only once or twice daily dosing for better compliance
• Reaches effective levels in blood and tissue with oral dosing
• Useful when injectable antibiotics are not practical

What Experts Say

Cefixime is a third generation cephalosporin antibiotic that stops bacteria from building their protective cell wall. This action kills susceptible bacteria rather than just slowing their growth, which makes it effective against many common respiratory and urinary pathogens seen in general practice.

Doctors in Pakistan commonly prescribe it for typhoid fever, given rising resistance to older first line antibiotics such as ampicillin and chloramphenicol. It works well against many gram negative organisms but has limited activity against some resistant strains, so lab testing is sometimes advised for severe cases.

Experts stress completing the full prescribed course even after symptoms improve within the first few days. Stopping early is a major driver of antibiotic resistance, which makes future infections harder to treat with standard oral drugs and can lead to relapse or complications later on.

Drug Class

• Third Generation Cephalosporin
• Antibiotic

Fixim Capsule 400mg formula

• Cefixime

Available forms

• Capsule

How to use Fixim Capsule 400mg?

• Take the capsule with or without food at evenly spaced times
• Swallow whole with a full glass of water
• Complete the entire course even if symptoms improve early
• Do not double the dose if you miss one, just take the next dose on time

Drug Interactions

• Warfarin: Cefixime can increase the blood thinning effect of warfarin, raising bleeding risk.
• Carbamazepine: Combined use may raise carbamazepine levels in the blood.
• Oral Contraceptives: Antibiotics may reduce the reliability of birth control pills during the course.
• Probenecid: This drug raises cefixime blood levels by slowing its clearance.

Risks and warnings

• Allergic Reactions: Avoid Fixim if you have a known allergy to cephalosporin or penicillin antibiotics.
• Diarrhea: Cefixime can disturb normal gut bacteria and cause loose stools or, rarely, severe colitis.
• Kidney Impairment: People with reduced kidney function may need a lower dose.
• Pregnancy: Use only if clearly needed and prescribed by a doctor.
• Antibiotic Resistance: Unnecessary or incomplete use encourages resistant bacteria to develop.

Fixim Capsule 400mg Side Effects

• Diarrhea or loose stools
• Nausea and stomach discomfort
• Headache
• Skin rash
• Vaginal itching or yeast infection in some women
• Rare severe allergic reaction with swelling and breathing difficulty

Storage Conditions

• Store below 30 degrees Celsius in a dry place
• Protect capsules from direct sunlight and moisture
• Keep out of reach of children
• Discard any unused capsules after the expiry date