Flexeril Capsule 400mg

About Flexeril Capsule 400mg

Flexeril Capsule 400mg Uses

• Typhoid fever
• Urinary tract infections
• Throat and tonsil infections (pharyngitis, tonsillitis)
• Bronchitis and other respiratory tract infections
• Middle ear infections (otitis media)
• Gonorrhea

Flexeril Capsule 400mg Benefits

• Once or twice daily dosing improves treatment adherence
• Effective against a wide range of common bacteria including typhoid causing Salmonella
• Can be taken with or without food
• Well suited for outpatient treatment of moderate infections

What Experts Say

Cefixime is a third generation oral cephalosporin that doctors commonly prescribe for typhoid fever in regions where resistance to older first line agents has become widespread. Its ability to reach effective concentrations in blood and tissue with simple once or twice daily dosing makes it a practical outpatient option compared with injectable alternatives.

Physicians usually confirm a bacterial diagnosis before starting cefixime, since it has no effect on viral illnesses and unnecessary use encourages resistance. A history of penicillin allergy is checked carefully as well, because a small percentage of patients with penicillin allergy can also react to cephalosporins due to a related chemical structure.

Doctors emphasize completing the full prescribed course even after symptoms settle, since stopping early is a recognized driver of relapse in typhoid treatment. Patients with kidney impairment may need a lower dose, and anyone who develops severe or bloody diarrhea during treatment should stop the medicine and seek medical advice promptly.

Drug Class

• Third generation cephalosporin antibiotic

Flexeril Capsule 400mg formula

• Cefixime

Available forms

• Capsule

How to use Flexeril Capsule 400mg?

• Take Flexeril Capsule 400mg exactly as prescribed by your doctor
• Swallow the capsule whole with a glass of water
• Can be taken with or without food
• Take doses at evenly spaced times each day
• Complete the full course even if symptoms improve early
• Do not double the dose if a dose is missed, take it as soon as you remember

Drug Interactions

• Probenecid: Increases cefixime blood levels and may prolong its effect.
• Warfarin: May increase the blood thinning effect and raise bleeding risk.
• Carbamazepine: Combined use may increase carbamazepine blood levels.
• Oral Typhoid Vaccine: Antibiotics can reduce the effectiveness of the live oral typhoid vaccine, avoid taking together.
• Hormonal Contraceptives: Antibiotic use may reduce the reliability of oral contraceptive pills.

Risks and warnings

• Allergy: Avoid if you have a known allergy to cefixime or other cephalosporin antibiotics.
• Penicillin Allergy: Use with caution in patients with a history of severe penicillin allergy due to possible cross reaction.
• Kidney Disease: Dose adjustment may be needed in patients with reduced kidney function.
• Diarrhea: Stop use and seek medical advice if severe or bloody diarrhea develops during or after treatment.
• Pregnancy and Breastfeeding: Use only if clearly needed and advised by a doctor.
• Diabetes: Cefixime can cause a false positive result on some urine glucose tests.

Flexeril Capsule 400mg Side Effects

• Diarrhea
• Abdominal pain
• Nausea
• Indigestion
• Headache
• Mild skin rash
• Loss of appetite
• Vaginal itching or yeast infection
• Severe allergic reactions such as swelling of the face or difficulty breathing
• Severe watery or bloody diarrhea signaling a C. difficile infection
• Yellowing of the skin or eyes signaling liver problems
• Blistering or peeling skin rash, rare but serious

Storage Conditions

• Store below 25°C in a cool dry place
• Keep capsules in their original blister pack away from moisture and light
• Keep out of reach of children
• Do not use after the expiry date printed on the pack