Ivatab Tablet 7.5mg

About Ivatab Tablet 7.5mg

Ivatab Tablet 7.5mg Uses

• Chronic stable angina pectoris in adults with normal sinus rhythm who cannot tolerate beta blockers
• Chronic stable angina as add on therapy when beta blockers alone do not control symptoms
• Chronic heart failure with reduced ejection fraction and a resting heart rate of 75 beats per minute or higher, alongside standard heart failure therapy
• Reducing the risk of hospital admission for worsening heart failure

Ivatab Tablet 7.5mg Benefits

• Lowers heart rate without significantly reducing blood pressure
• Eases the workload on the heart during angina episodes
• Improves exercise tolerance in patients with chronic stable angina
• Lowers the risk of hospitalization from worsening heart failure symptoms
• Suitable alternative for patients who cannot tolerate beta blocker side effects

What Experts Say

Cardiologists prescribe Ivatab for patients whose resting heart rate stays elevated despite standard treatment, since a heart rate above 70 beats per minute is linked to worse outcomes in both angina and heart failure. Ivabradine selectively slows the heart's natural pacemaker without lowering blood pressure, which suits patients who cannot tolerate beta blocker related fatigue or low blood pressure.

In heart failure with reduced ejection fraction, doctors add Ivatab on top of guideline based therapy including beta blockers and ACE inhibitors, once the patient is on a stable maximally tolerated beta blocker dose and heart rate remains high. Regular heart rate monitoring guides dose adjustment, since excessive bradycardia and a mildly increased risk of atrial fibrillation are the main concerns.

Doctors also counsel patients about phosphenes, brief flashes or brightness in vision caused by ivabradine acting on similar channels in the retina. These effects are usually mild and reversible once treatment stops, but patients are told to report them so the dose can be reassessed.

Drug Class

• If Channel Inhibitor (Cardiac Pacemaker Current Blocker)
• Heart Rate Lowering Agent, Non Beta Blocker Class

Ivatab Tablet 7.5mg formula

• Ivabradine Hydrochloride

Available forms

• Tablet

How to use Ivatab Tablet 7.5mg?

• Take Ivatab Tablet 7.5mg by mouth twice daily, with meals, since food improves absorption
• Swallow the tablet whole with a glass of water, do not crush or chew it
• Take doses at the same times each day, roughly 12 hours apart, for steady heart rate control
• Do not stop the medicine suddenly without consulting a doctor, since angina symptoms can worsen
• Follow the exact dose your doctor prescribes based on your resting heart rate and response

Drug Interactions

• Strong CYP3A4 Inhibitors: Ketoconazole, clarithromycin, and certain HIV protease inhibitors raise Ivatab blood levels and increase bradycardia risk, so combined use is avoided
• Strong CYP3A4 Inducers: Rifampicin and certain anti seizure drugs like phenytoin can reduce Ivatab effectiveness by speeding up its breakdown
• Other Heart Rate Lowering Drugs: Verapamil, diltiazem, and beta blockers combined with Ivatab raise the risk of excessive bradycardia
• QT Prolonging Medicines: Combining Ivatab with drugs that prolong the QT interval needs careful monitoring due to arrhythmia risk
• Grapefruit Juice: Large quantities can raise Ivatab blood levels and should be avoided

Risks and warnings

• Bradycardia: Ivatab can slow the heart rate excessively, especially when combined with other rate lowering drugs, and needs regular heart rate monitoring
• Visual Symptoms (Phosphenes): Some patients notice temporary brightness or flashes of light in their vision, usually mild and reversible, and should report this to their doctor if bothersome
• Atrial Fibrillation: Ivabradine slightly increases the risk of developing atrial fibrillation, so heart rhythm is monitored during treatment
• Liver And Kidney Impairment: Use with caution in significant liver or kidney disease, since dose adjustment may be needed
• Pregnancy And Breastfeeding: Not recommended during pregnancy or while breastfeeding due to potential harm to the baby
• Heart Block Or Sick Sinus Syndrome: Avoid in patients with certain conduction disorders unless a pacemaker is already fitted

Ivatab Tablet 7.5mg Side Effects

• Luminous visual phenomena (phosphenes) or blurred vision
• Slow heart rate (bradycardia)
• Headache
• Dizziness
• Palpitations or irregular heartbeat
• High blood pressure
• Nausea
• Shortness of breath
• Abnormal ECG findings
• Fatigue

Storage Conditions

• Store Ivatab Tablet 7.5mg at room temperature, below 30°C
• Keep the strip in its original blister pack, away from direct sunlight and moisture
• Keep out of reach of children
• Do not store in the bathroom or near a kitchen sink
• Discard any expired or unused tablets safely, do not flush them down the drain