Zestoretic 20

About Zestoretic 20

Zestoretic 20 Uses

• High blood pressure not controlled by a single medicine
• Long term blood pressure management
• Reducing strain on the heart from hypertension
• Combination therapy for patients needing two blood pressure medicines

Drug Class

• ACE inhibitor and thiazide diuretic combination
• Combination antihypertensive

What Experts Say

Lisinopril relaxes blood vessels by blocking a hormone that narrows them, while hydrochlorothiazide helps the kidneys remove extra salt and water.

Together they lower blood pressure more effectively than either medicine alone, which is why this combination is used once daily control is not enough with a single drug.

A dry cough or dizziness in the first few days is common, and blood pressure and kidney function are usually checked periodically during treatment.

Zestoretic 20 formula

• Lisinopril 20mg
• Hydrochlorothiazide 12.5mg

Available forms

• Tablet

How to use Zestoretic 20?

• Take one tablet once daily, at the same time each day.
• Swallow with water, with or without food.
• Rise slowly from sitting or lying down to avoid dizziness.
• Have your kidney function and electrolytes checked as advised.

Drug Interactions

Zestoretic 20 can interact with several common medicines.

• Potassium supplements or potassium sparing diuretics: Raises the risk of high potassium levels.
• Lithium: Increases lithium levels and toxicity risk.
• NSAIDs like ibuprofen: Can reduce the blood pressure lowering effect and stress the kidneys.

Risks and warnings

• Pregnancy: Strictly avoid, as it can seriously harm the developing baby.
• Swelling of the face or throat: Rare but serious reaction, needs emergency care.
• Kidney function: Requires monitoring, especially early in treatment.
• Low potassium or sodium: Hydrochlorothiazide can disturb electrolyte balance.

Zestoretic 20 Side Effects

• Dry cough
• Dizziness
• Low blood pressure
• Fatigue
• Electrolyte imbalance
• Increased urination

Storage Conditions

Store below 30°C in a dry place away from moisture and direct sunlight, out of reach of children.