Zestril Tablet 10mg

About Zestril Tablet 10mg

Zestril Tablet Uses

• Treating high blood pressure (hypertension)
• Managing chronic heart failure alongside other heart medicines
• Improving survival after a heart attack
• Protecting kidney function in people with diabetic kidney disease
• Lowering the risk of stroke linked to high blood pressure

Zestril Tablet Benefits

• Relaxes and widens blood vessels for smoother blood flow
• Eases the workload on the heart in heart failure patients
• Once daily dosing supports better treatment adherence
• Backed by decades of clinical use with a well established safety record
• Helps slow kidney damage caused by long standing diabetes

What Experts Say

Lisinopril works by blocking the angiotensin converting enzyme, which normally converts angiotensin I into angiotensin II, a hormone that narrows blood vessels and raises blood pressure. By interrupting this pathway, lisinopril allows blood vessels to relax and widen, lowering the pressure the heart needs to work against.

Clinical trials consistently show ACE inhibitors like lisinopril reduce cardiovascular events, slow the progression of heart failure, and improve survival rates after a heart attack. In patients with diabetes, lisinopril also lowers pressure inside the kidney filtering units, which slows the decline of kidney function over time.

Because lisinopril has a long half life, once daily dosing maintains steady blood pressure control throughout the day. The most reported side effect, a dry cough, occurs because ACE inhibition also raises bradykinin levels in the airways. Regular monitoring of kidney function and potassium is recommended during treatment.

Drug Class

• ACE Inhibitor (Angiotensin Converting Enzyme Inhibitor)

Zestril Tablet 10mg formula

• Lisinopril

Available forms

• Tablet

How to use Zestril Tablet 10mg?

• Take the tablet at the same time every day, with or without food
• Swallow the tablet whole with a full glass of water
• Do not skip doses even if blood pressure feels normal
• Follow the exact dose and schedule prescribed by your doctor
• Do not stop the medicine suddenly without medical advice

Drug Interactions

• Potassium Sparing Diuretics: Combined use with drugs like spironolactone raises the risk of high potassium levels
• NSAIDs: Medicines like ibuprofen or diclofenac can reduce the blood pressure lowering effect and affect kidney function
• Lithium: Lisinopril can raise blood lithium levels, increasing the risk of toxicity
• Diuretics: Combined use may cause an excessive drop in blood pressure
• Aliskiren: Increases the risk of hyperkalemia and kidney problems, especially in diabetic patients

Risks and warnings

• Pregnancy: Can cause fetal injury or death; avoid use during pregnancy, especially in the second and third trimester
• Kidney Impairment: Use with caution and a doctor supervised dose adjustment in reduced kidney function
• Angioedema: Stop the medicine immediately if swelling of the face, lips, tongue, or throat occurs
• Hyperkalemia: Monitor blood potassium levels closely, especially with kidney disease or potassium supplements
• Hypotension: May cause a marked drop in blood pressure, particularly after the first dose

Zestril Tablet Side Effects

• Dry, persistent cough
• Dizziness or lightheadedness
• Headache
• Fatigue
• Nausea
• Diarrhea
• Low blood pressure (hypotension)
• High potassium levels (hyperkalemia)
• Swelling of face, lips, tongue, or throat (angioedema)
• Changes in kidney function
• Chest pain
• Allergic skin reactions

Storage Conditions

• Store at room temperature between 15°C and 30°C
• Keep tablets in their original blister pack away from moisture
• Protect from direct sunlight and excess heat
• Keep out of reach of children
• Discard expired or unused tablets safely